Ultra-highly sensitive label-free AC quantum transistor for molecular diagnostics

• Grant number: 21/05058-3
• Support Opportunities: Regular Research Grants
• Start date: April 01, 2023
• End date: March 31, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Paulo Roberto Bueno
• Grantee: Paulo Roberto Bueno
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

This proposal is focused on the development of portable diagnostic assays for the rapid detection of molecules aiming at the diagnostics of diseases based on a new transduction signal and related device, which is one billion times more sensible than the preceding capacitive generation1 devel-oped by our research group. This transduction signal is based on the suitable chemical designing of interfaces that are able to operate within an alternate current (AC) quantum transistor characteristic. Hence, the purpose of the present research is to validate the AC quantum transistor methodology in the diagnostics of diseases using patient samples. (AU)