Interaction and effect of the COVID-19 pandemic on Tuberculosis control in the State of São Paulo: political-social, clinical-epidemiological aspects and innovative practices

• Grant number: 22/08510-7
• Support Opportunities: Research Projects - Thematic Grants
• Start date: December 01, 2023
• End date: November 30, 2028
• Field of knowledge: Health Sciences - Nursing - Public Health Nursing
• Principal Investigator: Ricardo Alexandre Arcêncio
• Grantee: Ricardo Alexandre Arcêncio
• Host Institution: Escola de Enfermagem de Ribeirão Preto (EERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Pesquisadores principais: Ione Carvalho Pinto ; Pedro Fredemir Palha
• Associated researchers: Aline Aparecida Monroe ; André da Silva Abade ; Antonio Ruffino Netto ; Dulce Maria de Oliveira Gomes ; Fabiana Costa Machado Zacharias ; Inês Santos Estevinho Fronteira ; Jaqueline Garcia de Almeida Ballestero ; Jason Edward Farley ; Javier Roger Raul Vargas Herrera ; Luciana Aparecida Fabriz ; Marcelino Santos Neto ; Marcos Augusto Moraes Arcoverde ; Mônica Cristina Ribeiro Alexandre D Auria de Lima ; Nancy Reynolds ; Nathalia Zini ; Regina Célia Fiorati ; Rubia Laine de Paula Andrade ; Sónia Maria Ferreira Dias ; Tatiana Ferraz de Araújo Alecrim ; Tereza Cristina Scatena Villa
• Associated research grant(s): 25/04927-9 - Advances in Research and International Academic-Scientific Integration between the Johns Hopkins School of Nursing and the Ribeirão Preto School of Nursing - USP., AV.EXT
• Associated scholarship(s): 25/05655-2 - Innovative practices in tuberculosis control: use of VDOT technology, in the context of the COVID 19 pandemic, BP.TT; 24/20603-6 - Tuberculosis and the SARS-CoV-2 pandemic: A time series study of vulnerable populations in the state of São Paulo, BP.IC; 24/14518-6 - Innovative practices in tuberculosis control: use of VDOT technology, in the context of the COVID 19 pandemic, BP.TT; + associated scholarships 24/04001-6 - Impact of the COVID-19 pandemic on the epidemiology of tuberculosis and its temporal trend in the State of São Paulo., BP.PD; 24/03738-5 - Innovative practices on Tuberculosis control: VDOT Technologies's use in the pandemic Covid 19 context, BP.PD; 24/03835-0 - Innovative practices in tuberculosis control: use of VDOT technology, in the context of the COVID 19 pandemic, BP.TT; 23/16905-4 - Impact of the COVID-19 pandemic on the epidemiology of tuberculosis and its temporal trend in the State of São Paulo., BP.DD - associated scholarships

Abstract

TB control may have been worsened by the COVID-19 pandemic, as a result of the focus and reorganization of health systems and services to deal with it. Objective: The study aims to assess the impact of the COVID-19 pandemic on tuberculosis prevention and control. Methods: The study will be carried out in the state of São Paulo and is structured in: Axis 1, political approach - interviews will be carried out with key informants from institutions, management and Social Movements, and official documents will be collected. The material corpus will be treated by Discourse Analysis. Axis 2, epidemiological aspects - there will be a survey of TB and COVID-19 data to form cohorts and assess the real impact of the COVID-19 pandemic on detection, treatment dropout and mortality by TB. Survival analysis, mixed effect models, interrupted time series and spatial analysis will be used. Axis 3, innovative practices - an evaluation of the cost-effectiveness of the Virtual-DOT (VDOT) strategy will be carried out, compared to Self-Administered Treatment and conventional Directly Observed Treatment, through a pragmatic study. For this, people with TB will be interviewed to survey the costs of using the application and to analyze the usability of the VDOT. For this axis, analysis of variance, Kruskal-Wallis test and application of a Mixed Effect Model will be used. Expected results: It is expected to produce and disseminate theoretical and operational knowledge involving the assessment of the impact of the COVID-19 pandemic on the prevention and control of TB, based on the analysis of political-social, clinical-epidemiological aspects and innovative practices for management of nursing care. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ALVES, YAN MATHIAS; BERRA, THAIS ZAMBONI; TAVARES, REGINALDO BAZON VAZ; ZINI, NATHALIA; FERREIRA, QUEZIA ROSA; ANDRADE, LICIA KELLEN DE ALMEIDA; TARTARO, ARIELA FEHR; PELODAN, MARIA EDUARDA PAGANO; VIGATO, BEATRIZ FORNAZIERO; SILVEIRA, BEATRIZ KURODA; et al. Vaccination Coverage at Birth in Brazil: Spatial and Temporal Trends in the Impact of COVID-19 on Uptake of BCG and Hepatitis B Vaccines. VACCINES, v. 12, n. 12, p. 13-pg., 2024-12-01. (22/08510-7, 23/01758-6)