DEVELOPMENT OF A NANOFORMULATION WITH ASSETS FROM BRAZILIAN BIODIVERSITY TO CONTROL PHYTOPATHOGENS IN FRUIT CULTURE

• Grant number: 24/07201-6
• Support Opportunities: Research Grants - Innovative Research in Small Business - PIPE
• Start date: January 01, 2025
• End date: December 31, 2026
• Field of knowledge: Biological Sciences - Botany - Applied Botany
• Principal Investigator: Erika Mattos Stein
• Grantee: Erika Mattos Stein
• Company: Prospecta - Pesquisa e Desenvolvimento de Bioinsumos Ltda
• CNAE: Pesquisa e desenvolvimento experimental em ciências físicas e naturais ; Atividades profissionais, científicas e técnicas não especificadas anteriormente
• Associated researchers: Marcio Henrique Zaim ; MURILO FAZOLIN
• Associated research grant: 22/02286-8 - Development of a nanoformulation with assets from brazilian biodiversity to control phytopathogens in fruit culture, AP.PIPE
• Associated scholarship(s): 24/23915-9 - Studies aimed at the development of a nanoformulation with essential oil of Piper aduncum L. (Piperaceae) for postharvest processing of papayas (Carica papaya L.)., BP.TT; 24/23913-6 - Development of a nanoformulation with assets from Brazilian biodiversity to control phytopathogens in fruit culture, BP.PIPE

Abstract

In order to evaluate the antifungal activity of the essential oil (EO) of a Brazilian plant against postharvest fungi of papaya, a series of assays were carried out in order to initially obtain the estimate of the effective concentration capable of inhibiting 50% of fungal development (EC50) using different isolates. At the same time, several tests were carried out for the development of 4 different formulations in nanostructured systems to carry the EO that were also tested for the inhibition of mycelial growth. Our results showed that the essential oil in its free form, added directly to the melting culture medium, was active at a certain concentration and this action was potentiated when used in formulation. In the in vivo assay with the fruits, it is possible to visualize the potential preventive and curative effect of the formulation on papayas against the inoculum without apparent phytotoxic effects on the skin of the fruits. Among the formulations evaluated, we will continue with one of them for the scaling stage, since it was very effective against all the isolates tested. In general, the incorporation of EO to the nanoformulations greatly enhanced the action of this active ingredient. (AU)