Exploiting magnetic properties for the development of modern extraction strategies e construction of sensors for analytical applications

• Grant number: 24/06616-8
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2025
• End date: January 31, 2027
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Diogo Librandi da Rocha
• Grantee: Diogo Librandi da Rocha
• Host Institution: Centro de Ciências Naturais e Humanas (CCNH). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil

Abstract

Dispersive liquid-liquid microextraction (DLLME) is used for rapid and efficient sample preparation with low solvent consumption. Automation of this process has been achieved in flow analysis systems with solenoid micro-pumps, allowing efficient online sample preparation. However, the analytical frequency could be improved with faster phase separation. Magnetic dispersive liquid-liquid microextraction (MLME) simplifies this separation using magnetic ionic liquids (MILs) as extractors. The aqueous phase is discarded while the organic phase is retained with the aid of a magnet. Although MLME has been applied in several analyses, it has not yet been explored for extractions in flow analysis systems. In this project, analytical procedures will be developed using MILs for MLME automation and sensor construction. A flow system with solenoid micro-pumps will be used for the determination of anionic surfactants in water. The organic phase will be retained by an electromagnet in a spectrophotometric cell constructed with 3D printing. Additionally, MLME will be evaluated in batch mode, with the organic phase being collected by a magnetic electrode for voltammetric determination of surfactants in water. MILs will also be studied as matrix for ion-selective membrane for the determination of calcium in foods and pharmaceutical preparations, aiming to replace conventional polymeric membranes. Parameters will be optimized to maximize extraction efficiency and analytical frequency with minimal consumption of reagents and solvents. The construction of the devices will also be optimized to improve portability and ease of construction. (AU)