Drug discovery consortium to develop new drugs for the treatment of tropical parasitic diseases

• Grant number: 25/01873-5
• Support Opportunities: Research Grants - Research Partnership for Technological Innovation - PITE
• Start date: January 01, 2026
• End date: June 30, 2029
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Luiz Carlos Dias
• Grantee: Luiz Carlos Dias
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated researchers: Adriano Defini Andricopulo ; Anna Caroline Campos Aguiar ; Carolina Borsoi Moraes ; Jadel Müller Kratz ; Leonardo Luiz Gomes Ferreira ; Luiza dos Reis Cruz ; Rafael Consolin Chelucci ; Rafael Victorio Carvalho Guido
• Associated research grant: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery, AP.CEPID

Abstract

This proposal targets activities that would support the continuation of the FAPESP/MMV/DNDi/UNICAMP/USP consortium (MINDI) with the aim of discovering drug candidates for malaria and Chagas disease. The consortium, composed of researchers from the state of São Paulo with a proven track record of producing high-quality research, working in collaboration with scientists experienced in drug discovery from Drugs for Neglected Diseases initiative (DNDi, www.dndi.org) and the Medicines for Malaria Venture (MMV, www.mmv.org), was established with the support of FAPESP and today plays a leading role in the field of drug discovery for these diseases in the country. The proposed project aims to strengthen the consortium and identify late leads or candidates for preclinical development, which would represent a great scientific achievement with the potential of a significant positive impact for society. (AU)