Animal reproduction and production: the maternal-fetal dialogue in ruminants and its impact on the Brazilian cattlefarming economy

• Grant number: 02/00233-0
• Support Opportunities: Research Projects - Thematic Grants
• Start date: May 01, 2003
• End date: April 30, 2008
• Field of knowledge: Agronomical Sciences - Veterinary Medicine
• Principal Investigator: Maria Angelica Miglino
• Grantee: Maria Angelica Miglino
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Pesquisadores principais: Mario Binelli ; Pedro Primo Bombonato
• Associated research grant(s): 05/54666-3 - Alan Conley | University California Davis - Estados Unidos, AV.EXT; 04/03277-4 - Vibeke dantzer | the royal veterinary and agricultural university - Dinamarca, AV.EXT; 04/03276-8 - Anthony Michael Carter | Inst. of Medical Biology/University of Southern Denmark - Dinamarca, AV.EXT
• Associated scholarship(s): 08/00051-6 - ISOLATION, CULTURE, AND DIFFERENTIATION OF STEM CELLS FROM THE HEPATIC BUD FOR CELLULAR THERAPY UTILIZATION, BP.PD

Abstract

The bovine herd is unquestionably the largest addition of ruminants exploited in extensive conditions in Brazil, due to their extreme rusticity demonstrated when submitted to areas of arid climate and low nutritional value postures. Often bovines can even make use of non-agricultural soils or soils of unfavorable topography soils. The bubaline herd, in particular, is raised in flooded or marsh lands inappropriate for the exploration of other species. Even under such adverse conditions these animals demonstrate a high zootechnological performance, which favors their sustained development and the quality improvement of life in poor brazilians regions lacking in economic alternatives. In Brazil, particularly in São Paulo, several laboratories are equipped to conduct research on reproduction and related subjective. Nevertheless, their activities are concentrated on the embryo it self with no attention to their fatal membrane. Worth pointing out is the fact that the further technology advances in this area and more already is there to do. Relatives questions about shape and functions of trophoblastic cells, pregnant signalization and pathologies, substance transfers through placental barrier, placental hormones, genetics factors relatives the embryonic development, the characterization into the uterine micro environment, cloned cattle placentation and angiogenesis still they remain open to the research constituting clear that when evident much could contribute for the supported cattle development. Looking for to concentrate itself in the embryonic development, without interim to all disrespect part of its, essential to its development (fetal membranes), and, on the other hand attempting the embryonic dynamics of this part of all the NERPA if it organized as core of studies. It is with this purpose that NERPA puts forwards its proposals of binomial reproductive efficiency x placenta retention and expands its objectives beyond the gross and microscopic characterization of the cotyledonal type and synepthelicorial placenta. The understanding of the sub cellular and molecular organism of the various types of tissue and trophoblast cells of the bovines and bubaline is fundamental and, why not go further, characterizing the proper uterine environment in the begin of gestation, as well as, to include genomic techniques related to embryonic development velocity in this animals. Naturally these functional aspects of the placental barrier, as well as, the capacity of transfer substances during the pregnancy equally they will be contemplated... (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ASSIS NETO, A. C.; PEREIRA, F. T. V.; SANTOS, T. C.; AMBROSIO, C. E.; LEISER, R.; MIGLINO, M. A.. Morpho-physical Recording of Bovine Conceptus (Bos indicus) and Placenta from Days 20 to 70 of Pregnancy. REPRODUCTION IN DOMESTIC ANIMALS, v. 45, n. 5, p. 760-772, OCT 2010. (02/00233-0)