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The production of amino acid chelates from hydrolyzed proteid of Saccharomyces cerevisiae to be used as mineral food supplements of high bio-availability

Grant number: 00/12797-0
Support Opportunities:Research Grants - Innovative Research in Small Business - PIPE
Start date: July 01, 2001
End date: December 31, 2004
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Technology
Principal Investigator:Ricardo da Silva Sercheli
Grantee:Ricardo da Silva Sercheli
Company:NPA Núcleo de Pesquisas Aplicadas Ltda
City: Jaboticabal

Abstract

The goal is to develop processes aimed at the industrial production of chelates of amino acids obtained through complexation reactions between different metals and the hydrolyzed proteid of Saccharomyces cerevisiae. Stage 1: Hydrolyzed proteid of Saccharomyces cerevisiae: though amply described in technical literature, the research intends to develop an industrial process capable of obtaining a hydrolyzed product of the necessary quality to be used in the next stage, at a competitive operational cost, avoiding the generation of effluents. The two selected processes for the study were that of acid hydrolysis and of enzyme hydrolysis: a) acid hydrolysis: the work will initially concentrate on the parameters described in the literature, aiming for an optimization of the process in relation to the different acids used; b) enzyme hydrolysis: will be conducted in the presence of a mixture of proteids, initially following the data described in the literature for posterior determination of the operational parameters of the process. The choice of the best process will be made based on the quality and cost of the hydrolysis obtained. Stage 2: amino acid chelates. These will be obtained by adopting the following steps: a) the formation of organo-metallic complexes; b) desalinization of the mother liquid of the reaction and the isolation of the product; c) the drying of the complex. Phase 2 of the project will seek, taking into account the results obtained in phase 1 and works described in the literature, to develop processes aimed at the industrial production of free amino acid chelates and peptides obtained through complexation reactions between different metals and the hydrolyzed proteid of Saccharomyces cerevisiae. The proposal is to obtain a hydrolyzed proteid containing peptides with a molecular weight of half 1 million daltons, which offer high absorption for the organism. (AU)

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