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Implantable electromagnetic propulsion systems for uni and biventricular or artifical heart blood circulatory assist devices

Grant number: 06/58773-1
Support type:Research Projects - Thematic Grants
Duration: December 01, 2007 - November 30, 2012
Field of knowledge:Engineering - Electrical Engineering
Principal Investigator:José Roberto Cardoso
Grantee:José Roberto Cardoso
Home Institution: Escola Politécnica (EP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Co-Principal Investigators:Aron Jose Pazin de Andrade ; Jarbas Jakson Dinkhuysen
Associated grant(s):08/53611-9 - Laurent Krahenbuhl | École Centrale de Lyon - France, AV.EXT
Associated scholarship(s):11/22972-9 - Transcutaneous energy transmitter model parameter determination by stochastic optimization methods, BP.IC
11/18341-3 - Project of a transcutaneous energy transmitter to supply power to ventricular auxiliary device, BP.DR

Abstract

Brazil has contributed for the world development of cardiology, especially in the cardiac surgery field. The improvement of surgical techniques makes possible to perform several successful heart transplantations in Brazil. However, the number of cardiac donors is lower than the number of candidates for heart transplantation. Consequently many patients die waiting for an organ. To support those patients, the leading international institutions are developing several different ventricular assist devices (V AD) like artificial ventricles, total artificial hearts, axial pumps and implantable centrifugal pumps. The implantable centrifugal pumps have high durability, more than 2 years. One problem is that the commercially available pulsate VADs are not really available, or even accessible, for Brazilian patients. About 62,000 cardiac surgeries by year are performed in Brazil, 47.000 using extracorporeal circulation. We estimate that 2000 patients could be potential candidates for a VAD implantation. Therefore, became very important to improve the VAD's research areas and develop our own technology with accessible price for Brazilian people. The objective of this project is to improve this research area, studding and developing an implantable centrifugal blood pump for long term ventricular assistance as well its surgical procedures. During the initial phase of tests with the prototypes, functional simulations and in vitro studies will be performed. On the second phase of tests, animal in vivo experiments will be performed. Many multi-disciplinary research groups will participate on this study as well as: physicians, surgeons, veterinarians, mechanical and electronic engineers and biologists, from different institutions as: IDPC, USP, UNICAMP, ITA, USJT and UFMG, making integration work for scientific and technical improvement with high national and international relevancy. (AU)

Articles published in Agência FAPESP Newsletter about the research grant
Scientists in Brazil develop an artificial implantable heart 
Articles published in Pesquisa FAPESP Magazine about the research grant:
Artificial Heart 

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA SILVA, ISAIAS; HORIKAWA, OSWALDO; CARDOSO, JOSE R.; CAMARGO, FERNANDO A.; ANDRADE, ARON J. P.; BOCK, EDUARDO G. P. Single Axis Controlled Hybrid Magnetic Bearing for Left Ventricular Assist Device: Hybrid Core and Closed Magnetic Circuit. ARTIFICIAL ORGANS, v. 35, n. 5, p. 448-453, MAY 2011. Web of Science Citations: 2.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.