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NICT of Complex Fluids (IFCx)


We propose the establishment of the NICT of Complex Fluids (IFCx), with the purpose of congregating researchers in the areas of physics, chemistry, biology, immunology, medicine, dentistry, and, mathematics, working on problems associated with complex fluids. The IFCx will have activities of research, teaching, and extension. The research activities are directed to the generation of knowledge in the frontiers of science, within a strong multidisciplinary environment. The IFCx will organize periodic Schools and will foster the creation of new undergraduate and graduate courses inits areas of research. It will work at the level of high-school teaching, at least in some larger centers, to organize recycling courses for teachers in topics of structure of matter, new materials, water, and biological fluids. As the main goals of study, we have chosen three families of complex fluids, liquid crystals, magnetic colloids, and fluids of biological interest, which are suitable for an integrated approach involving several specialties. In the biological area, there will be emphasis on investigations of interaction, structure, and function, of Iipids and proteins, with attention to artificial and cell membranes. Liquid crystals bring the concepts of orientation and position ordering of their basic units, in different size scales. Some liquid crystals are formed in processes of self-organization, and are similar to cell structures, as the membranes of phospholipids; biological processes may be investigated on the basis of theories developed to explain phase transitions in Iiquid crystals. Magnetic colloids are unique systems of investigation, with the fluidity of an isotropic Iiquid and large magnetic susceptibility. Besides numerous industrial applications, ferrofluids have been used as carriers of drugs in medical treatments and as elements of contrast to obtain in vivo images. In the area of biological fluids, we will pay special attention to human proteins, with investigations of stability and the process of oxidation. In this case, there is an immediate interface with the Iyotropic liquid crystals. The general goals of the IFCx may be grouped in blocs, at short, medium, and long times. At short time, we plan to carry out a multidisciplinary investigation of complex fluids. At medium time, we plan the formation of students with a multidisciplinary background, the organization of an articulated network of laboratories, with the possibility of investigating different problems with complementary experimental techniques, and the development of extension activities involving most of the specialties of the present proposal. At long run, we plan to give emphasis to both the formation of students and the activities of extension; depending on the novelty and the applicability of our results in the area of fluids of biological interest, in particular lipoproteins, we plan to develop new methods of diagnostic of atherosclerosis and suggest clinical treatments. The production of bibliographical material, besides the regular publication of scientific articles, is another purpose of this proposal. These goals can be reached by articulated activities: course and schools, for a better understanding of research problems and the formation of students; organization of special courses on the common experimental techniques, for the training of new users of the available equipment; meetings and workshops with the members of IFCx, and with focus on specific problems; improvements in the internet site for better interactions within the IFCx and with the external public; proposal and improvement of methodologies to study lipoproteins. (AU)

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Scientific publications (15)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ALVES, S.; FIGUEIREDO NETO, A. M.. Advances in the non-linear optical investigation of lyotropic-like low-density human lipoproteins in the native and oxidised states. LIQUID CRYSTALS, v. 41, n. 3, p. 465-470, . (08/57685-7)
KASMAS, S. H.; IZAR, M. C.; FRANCA, C. N.; RAMOS, S. C.; MOREIRA, F. T.; HELFENSTEIN, T.; MORENO, R. A.; BORGES, N. C.; FIGUEIREDO-NETO, A. M.; FONSECA, F. A.. Differences in synthesis and absorption of cholesterol of two effective lipid-lowering therapies. Brazilian Journal of Medical and Biological Research, v. 45, n. 11, p. 1095-1101, . (08/57685-7)
CARTOLANO, FLAVIA DE C.; DIAS, GABRIELA D.; DE FREITAS, MARIA C. P.; FIGUEIREDO NETO, ANTONIO M.; DAMASCENO, NAGILA R. T.. Insulin Resistance Predicts Atherogenic Lipoprotein Profile in Nondiabetic Subjects. JOURNAL OF DIABETES RESEARCH, . (11/13616-4, 08/57685-7, 11/12523-2, 15/06222-0)
SALVADOR, MARCELO; NICOLAO, LUCAS; FIGUEIREDO, W.. Competing cubic and uniaxial anisotropies on the energy barrier distribution of interacting magnetic nanoparticles. Physical Review B, v. 100, n. 10, . (08/57685-7)
NAYARA D. MASSUNAGA; CAROLINA N. FRANÇA; HENRIQUE T. BIANCO; CARLOS E.S. FERREIRA; JULIANA T. KATO; RUI M.S. PÓVOA; ANTONIO M. FIGUEIREDO NETO; MARIA CRISTINA O. IZAR; FRANCISCO ANTONIO HELFENSTEIN FONSECA. Circulating microparticles and central blood pressure according to antihypertensive strategy. Clinics, v. 74, . (08/57685-7)
GONCALVES, EDUARDO S.; COCCA, LEANDRO H. Z.; ARAUJO, WAGNER W. R.; PAREKH, KINNARI; OLIVEIRA, CRISTIANO L. P.; SIQUEIRA, JONATHAS P.; MENDONCA, CLEBER R.; DE BONI, LEONARDO; NETO, ANTONIO M. FIGUEIREDO. Influence of Magnetic Field on the Two-Photon Absorption and Hyper-Rayleigh Scattering of Manganese-Zinc Ferrite Nanoparticles. Journal of Physical Chemistry C, v. 124, n. 12, p. 6784-6795, . (08/57685-7, 11/13616-4, 14/50983-3, 16/20886-1, 18/11283-7)
ANTONOVA, A. M.; BARBERO, G.; BATALIOTO, F.; NETO, A. M. FIGUEIREDO; PAREKH, K.. Electric response of cells containing ferrofluid particles. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 856, . (08/57685-7, 11/13616-4)
GONCALVES, E. S.; FONSECA, R. D.; DE BONI, L.; FIGUEIREDO NETO, A. M.. Tuning hyper-Rayleigh scattering amplitude on magnetic colloids by means of an external magnetic field. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, v. 35, n. 11, p. 2681-2689, . (08/57685-7, 11/13616-4, 15/20555-2, 16/20886-1)
AKPINAR, EROL; YURDAKUL, SINAN; FIGUEIREDO NETO, ANTONIO MARTINS. Comparison between lyotropic cholesteric phase behavior with partly fluorinated surfactants and their exact hydrogenated counterparts. JOURNAL OF MOLECULAR LIQUIDS, v. 259, p. 239-248, . (11/13616-4, 08/57685-7, 14/50983-3)
ESPINOSA, D. H. G.; OLIVEIRA, C. L. P.; FIGUEIREDO NETO, A. M.. Influence of an external magnetic field in the two-photon absorption coefficient of magnetite nanoparticles in colloids and thin films. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, v. 35, n. 2, p. 346-355, . (08/57685-7, 11/13616-4)
BATALIOTO, F.; FIGUEIREDO NETO, A. M.; BARBERO, G.. Random Energy Barrier Model for AC Electrode Conductivity. Journal of Physical Chemistry C, v. 123, n. 11, p. 6650-6654, . (08/57685-7, 11/13616-4)
COSTA, EDNA S.; FRANCA, CAROLINA N.; FONSECA, FRANCISCO A. H.; KATO, JULIANA T.; BIANCO, HENRIQUE T.; FREITAS, THIAGO T.; FONSECA, HENRIQUE A. R.; FIGUEIREDO NETO, ANTONIO MARTINS; IZAR, MARIA CRISTINA. Beneficial effects of green banana biomass consumption in patients with pre-diabetes and type 2 diabetes: a randomised controlled trial. BRITISH JOURNAL OF NUTRITION, v. 121, n. 12, p. 1365-1375, . (08/57685-7)
SALVADOR, MARCELO; NICOLAO, LUCAS; FIGUEIREDO, W.. Thermal relaxation in a disordered one-dimensional array of interacting magnetic nanoparticles. Journal of Magnetism and Magnetic Materials, v. 538, . (08/57685-7)
DOMINGUES, TATIANA M.; PEREZ, KATIA R.; MIRANDA, ANTONIO; RISKE, KARIN A.. Comparative study of the mechanism of action of the antimicrobial peptide gomesin and its linear analogue: The role of the beta-hairpin structure. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1848, n. 10, A, p. 2414-2421, . (08/57685-7, 12/10442-8)
FONSECA, HENRIQUE ANDRADE R.; FONSECA, FRANCISCO A.; LINS, LIVIA C.; MONTEIRO, ANDREA M.; BIANCO, HENRIQUE T.; BRANDAO, SERGIO A.; POVOA, RUI M.; JULIANO, LUIZ; FIGUEIREDO-NETO, ANTONIO M.; BOSCHCOV, PAULO; et al. Antihypertensive therapy increases natural immunity response in hypertensive patients. Life Sciences, v. 143, p. 124-130, . (08/57685-7)

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Filed patent(s) as a result of this research project

GRAXAS MAGNÉTICAS LUBRIFICANTES, PROCESSO DE SÍNTESE DA MESMA E SEU USO BR1020130153079 - Universidade de São Paulo (USP) . Giancarlo Espósito de Souza Brito ; Antonio Martins Figueiredo Neto - June 2013, 18