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Development and application of microfluidic devices for electrophoresis with electrochemical detection

Grant number: 06/03317-1
Support type:Regular Research Grants
Duration: February 01, 2007 - March 31, 2009
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Principal Investigator:Dosil Pereira de Jesus
Grantee:Dosil Pereira de Jesus
Home Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

In this project microfluidic devices for electrophoresis will be manufactured on glass and/or polymeric substrates. A simple microfabrication technique, involving laser-printing toner (as structural material) depositition, and conventional ones, such as lithography will be used. Electrochemical detection (contactless conductometric and amperometric) will be implemented and evaluated in the microdevices. Electrokinetic and hydrodynamic sample injection systems will be developed in order to attain analysis with good precision and accuracy. Finally, methods for electrophoresis separation in the microdevices will be developed for determination of several compounds in samples of food, biological fluids, and others. (AU)