Laminar corium histopathology after experimental intestinal ischemic/reperfusion, in horses

• Grant number: 07/01604-6
• Support Opportunities: Regular Research Grants
• Start date: January 01, 2008
• End date: June 30, 2009
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Carlos Augusto Araújo Valadão
• Grantee: Carlos Augusto Araújo Valadão
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

Equine acute laminitis is a highly debilitating disease of the digital soft tissues. Two main theories regarding its pathophysiology state that blood flow alterations and laminar basement membrane breakdown are involved in the establishment of this severe disease. Laminitis usually occurs secondary to other diseases such as acute gastrointestinal tract disease (colic). The pathophysiology, and therefore the treatment, of equine laminitis has been a source of controversy in the last few years. The purpose this study is to evaluated histological techniques and though the enzymatic measurement the possible alterations caused in the laminar corium during the intestinal ischemia reperfusion injury in horses treated or not with hydrocortisone. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LUCIANE M. LASKOSKI; ROSANGELA LOCATELLI-DITTRICH; RENATO S. SOUSA; JULIANA S. BRUM; THIERRY G. CRISTO; FABIANO MONTIANI-FERREIRA; OLAIR C. BELTRAME; CARLOS A.A. VALADÃO. Lesões laminares em cavalos com estresse oxidativo sistêmico, acometidos por doenças gastrintestinais experimentalmente induzidas ou de ocorrência natural. Pesquisa Veterinária Brasileira, v. 36, n. 8, p. 694-700, 2016-08-00. (07/01604-6, 06/05271-9)