Generation of human artificial skins and invasive melanomas as a platform for pharmacological testing

• Grant number: 08/58817-4
• Support Opportunities: Regular Research Grants
• Duration: April 01, 2009 - June 30, 2011
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Principal Investigator: Silvya Stuchi Maria-Engler
• Grantee: Silvya Stuchi Maria-Engler
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; PIRES CAMILLO, MARIA APARECIDA; MARIA-ENGLER, SILVYA STUCHI; GRASSI RICI, ROSE ELI; SOUZA SARKIS, JORGE EDUARDO; MARIA, DURVANEI AUGUSTO. Boron uptake in normal melanocytes and melanoma cells and boron biodistribution study in mice bearing B16F10 melanoma for boron neutron capture therapy. RADIATION AND ENVIRONMENTAL BIOPHYSICS, v. 51, n. 3, p. 319-329, AUG 2012. (08/58817-4)

BROHEM, CARLA A.; MASSARO, RENATO R.; TIAGO, MANOELA; MARINHO, CAMILA E.; JASIULIONIS, MIRIAM G.; DE ALMEIDA, REBECA L.; RIVELLI, DIOGO P.; ALBUQUERQUE, RENATA C.; DE OLIVEIRA, TIAGO F.; DE MELO LOUREIRO, ANA P.; et al. Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death. PIGMENT CELL & MELANOMA RESEARCH, v. 25, n. 3, p. 354-369, MAY 2012. (08/58817-4, 06/50479-7, 09/54816-6)

DA SILVA CARDEAL, LAURA BEATRIZ; BOCCARDO, ENRIQUE; TERMINI, LARA; RABACHINI, TATIANA; ANDREOLI, MARIA ANTONIETA; DI LORETO, CELSO; LONGATTO FILHO, ADHEMAR; VILLA, LUISA LINA; MARIA-ENGLER, SILVYA STUCHI. HPV16 Oncoproteins Induce MMPs/RECK-TIMP-2 Imbalance in Primary Keratinocytes: Possible Implications in Cervical Carcinogenesis. PLoS One, v. 7, n. 3, MAR 16 2012. (08/58817-4, 08/03232-1)

BROHEM, CARLA A.; DA SILVA CARDEAL, LAURA B.; TIAGO, MANOELA; SOENGAS, MARIA S.; DE MORAES BARROS, SILVIA B.; MARIA-ENGLER, SILVYA S.. Artificial skin in perspective: concepts and applications. PIGMENT CELL & MELANOMA RESEARCH, v. 24, n. 1, p. 35-50, FEB 2011. (08/58817-4, 06/50479-7)

RENATO RAMOS MASSARO; CARLA ABDO BROHEM; REBECA LEITE DE ALMEIDA; DIOGO PINEDA RIVELLI; JULIANO ANDREOLI MIYAKE; ALISON COLQUHOUN; SILVIA BERLANGA DE MORAES BARROS; SILVYA STUCHI MARIA-ENGLER. 4-Nerolidylcatechol induces autophagy in human glioblastoma cells. Brazilian Journal of Pharmaceutical Sciences, v. 53, n. 3, 2018-02-01. (08/58817-4)

MATHEUS, ERIKA R.; ZONTA, MARCO A.; DISCACCIATI, MICHELLE G.; PARUCI, PRISCILA; VELAME, FERNANDA; CARDEAL, LAURA B. S.; BARROS, SILVIA B. M.; PIGNATARI, ANTONIO C.; MARIA-ENGLER, SILVYA S.. MMP-9 Expression Increases According to the Grade of Squamous Intraepithelial Lesion in Cervical Smears. DIAGNOSTIC CYTOPATHOLOGY, v. 42, n. 10, p. 827-833, OCT 2014. (08/58817-4, 12/09746-2)

FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; MARIA-ENGLER, SILVYA STUCHI; SOTO-CERRATO, VANESSA; PEREZ-TOMAS, RICARDO; MARIA, DURVANEI AUGUSTO. The curcumin analog DM-1 induces apoptotic cell death in melanoma. TUMOR BIOLOGY, v. 34, n. 2, p. 1119-1129, APR 2013. (08/58817-4, 11/50435-8)

FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; MARIA-ENGLER, SILVYA STUCHI; TIAGO, MANOELA; CAPELOZZI, VERA LUIZA; GIORGI, RICARDO RODRIGUES; MARIA, DURVANEI AUGUSTO. Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy. PLoS One, v. 8, n. 3, MAR 20 2013. (08/58817-4)