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Generation of human artificial skins and invasive melanomas as a platform for pharmacological testing

Grant number: 08/58817-4
Support type:Regular Research Grants
Duration: April 01, 2009 - June 30, 2011
Field of knowledge:Biological Sciences - Biochemistry
Principal Investigator:Silvya Stuchi Maria-Engler
Grantee:Silvya Stuchi Maria-Engler
Home Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Articles published in Pesquisa FAPESP Magazine about the research grant:
Laboratory Skin 
Recreated skin 

Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MATHEUS, ERIKA R.; ZONTA, MARCO A.; DISCACCIATI, MICHELLE G.; PARUCI, PRISCILA; VELAME, FERNANDA; CARDEAL, LAURA B. S.; BARROS, SILVIA B. M.; PIGNATARI, ANTONIO C.; MARIA-ENGLER, SILVYA S. MMP-9 Expression Increases According to the Grade of Squamous Intraepithelial Lesion in Cervical Smears. DIAGNOSTIC CYTOPATHOLOGY, v. 42, n. 10, p. 827-833, OCT 2014. Web of Science Citations: 5.
FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; MARIA-ENGLER, SILVYA STUCHI; SOTO-CERRATO, VANESSA; PEREZ-TOMAS, RICARDO; MARIA, DURVANEI AUGUSTO. The curcumin analog DM-1 induces apoptotic cell death in melanoma. TUMOR BIOLOGY, v. 34, n. 2, p. 1119-1129, APR 2013. Web of Science Citations: 15.
FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; MARIA-ENGLER, SILVYA STUCHI; TIAGO, MANOELA; CAPELOZZI, VERA LUIZA; GIORGI, RICARDO RODRIGUES; MARIA, DURVANEI AUGUSTO. Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy. PLoS One, v. 8, n. 3 MAR 20 2013. Web of Science Citations: 12.
FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; PIRES CAMILLO, MARIA APARECIDA; MARIA-ENGLER, SILVYA STUCHI; GRASSI RICI, ROSE ELI; SOUZA SARKIS, JORGE EDUARDO; MARIA, DURVANEI AUGUSTO. Boron uptake in normal melanocytes and melanoma cells and boron biodistribution study in mice bearing B16F10 melanoma for boron neutron capture therapy. RADIATION AND ENVIRONMENTAL BIOPHYSICS, v. 51, n. 3, p. 319-329, AUG 2012. Web of Science Citations: 4.
BROHEM, CARLA A.; MASSARO, RENATO R.; TIAGO, MANOELA; MARINHO, CAMILA E.; JASIULIONIS, MIRIAM G.; DE ALMEIDA, REBECA L.; RIVELLI, DIOGO P.; ALBUQUERQUE, RENATA C.; DE OLIVEIRA, TIAGO F.; DE MELO LOUREIRO, ANA P.; OKADA, SABRINA; SOENGAS, MARIA S.; DE MORAES BARROS, SILVIA B.; MARIA-ENGLER, SILVYA S. Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death. PIGMENT CELL & MELANOMA RESEARCH, v. 25, n. 3, p. 354-369, MAY 2012. Web of Science Citations: 27.
DA SILVA CARDEAL, LAURA BEATRIZ; BOCCARDO, ENRIQUE; TERMINI, LARA; RABACHINI, TATIANA; ANDREOLI, MARIA ANTONIETA; DI LORETO, CELSO; LONGATTO FILHO, ADHEMAR; VILLA, LUISA LINA; MARIA-ENGLER, SILVYA STUCHI. HPV16 Oncoproteins Induce MMPs/RECK-TIMP-2 Imbalance in Primary Keratinocytes: Possible Implications in Cervical Carcinogenesis. PLoS One, v. 7, n. 3 MAR 16 2012. Web of Science Citations: 34.
BROHEM, CARLA A.; DA SILVA CARDEAL, LAURA B.; TIAGO, MANOELA; SOENGAS, MARIA S.; DE MORAES BARROS, SILVIA B.; MARIA-ENGLER, SILVYA S. Artificial skin in perspective: concepts and applications. PIGMENT CELL & MELANOMA RESEARCH, v. 24, n. 1, p. 35-50, FEB 2011. Web of Science Citations: 79.

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