Expression analysis center of the clinical genome project: the role of chemokines, adhesion molecules and angiogenesis-related genes in cancer

• Grant number: 02/01511-4
• Support Opportunities: Genome Research Grants
• Start date: November 01, 2002
• End date: March 31, 2005
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Marco Antonio Zago
• Grantee: Marco Antonio Zago
• Host Institution: Hemocentro de Ribeirão Preto. Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da USP (HCMRP). Secretaria da Saúde (São Paulo - Estado). Ribeirão Preto , SP, Brazil

Abstract

We propose to use the resources of our Laboratories and of our Bioinformatics group to coordinate and integrate the activities of two expression analysis laboratories and two general genome analysis laboratories to: 1) Prepare high quality mRNA from tissue samples for expression analysis; 2) Prepare DNA from tissue and blood samples (from patients and controls); 3) Carry on micro-array hybridization and analysis; 4) Coordinate the analysis of polymorphisms in DNA from blood samples from patients and from controls; 5) Coordinate the high-throughput analysis to detect loss of heterozygosity; 6) Develop the research project for downstream exploitation of the data "Role of chemokines, adhesion molecules and angiogenesis-related genes in cancer". (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ALVES, V. A. F.; NONOGAKI, S.; CURY, P. M.; WUENSCH-FILHO, V.; DE CARVALHO, M. B.; MICHALUART-JUNIOR, P.; MOYSES, R. A.; CURIONI, O. A.; FIGUEIREDO, D. L. A.; SCAPULATEMPO-NETO, C.; et al. Annexin A1 subcellular expression in laryngeal squamous cell carcinoma. Histopathology, v. 53, n. 6, p. 715-727, DEC 2008. (02/01511-4, 02/07304-0, 02/01520-3, 04/12054-9)