Neuropsychological profile of adolescents exposed to situations of early emotional stress

• Grant number: 10/18374-6
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2011
• End date: February 28, 2013
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Sandra Scivoletto
• Grantee: Sandra Scivoletto
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Carolina Fuentes Moreira ; Giovanna Kliemann Scarpari ; Paula Approbato de Oliveira ; Paulo Jannuzzi Cunha

Abstract

The literature suggests that exposure to situations of stress can cause many severe alterations in biological, emotional and social development of individuals, especially in childhood and adolescence, which are periods of neurobiological and cognitive functions development. This research aims to investigate the neuropsychological functioning of adolescents exposed to situations of early emotional stress such as maltreatment, sexual abuse, neglect and other types of domestic violence during childhood, as well as studying the relationships between these experiences, existence of psychiatric disorders and objective measures of stress levels (salivary cortisol). Thirty adolescents between 12 to 16 years of age, who had faced situations of early emotional stress, will be submitted to psychiatric evaluation and a battery of comprehensive neuropsychological evaluation, which will consist of the assessment of attention, verbal and visual memory, information processing, learning capacity, executive functions and decision making. The cognitive performance of this group will be compared to a control group of 30 adolescents with the same age, socio-economic and educational status, but that has not been submitted to situations of stress. In both groups, interviews will be conducted with the subjects themselves and family and / or legal guardians, in order to carefully delineate the history of each one of them and eligibility for the study. Each one will be submitted to instruments of quantitative and qualitative assessment of stressful situations, which will be analyzed for possible correlations between these experiences and possible cognitive changes that have been found. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SANDRA SCIVOLETTO; THIAGO F SILVA; PAULO JANNUZZI CUNHA; ROBERT A ROSENHECK. The impact of psychiatric diagnosis on treatment adherence and duration among victimized children and adolescents in São Paulo, Brazil. Clinics, v. 67, n. 1, p. 3-9, 2012-00-00. (10/15604-0, 10/18374-6, 10/15786-1)

SCIVOLETTO, SANDRA; DE MEDEIROS FILHO, MAURO VITOR; STEFANOVICS, ELINA; ROSENHECK, ROBERT A.. Challenges in Developing a Community-Based Program for Maltreated Children and Adolescents in Brazil. PSYCHIATRIC SERVICES, v. 65, n. 2, p. 138-140, FEB 2014. (10/18374-6)

OMETTO, MARIELLA; DE OLIVEIRA, PAULA APPROBATO; MILIONI, ANA LUIZA; DOS SANTOS, BERNARDO; SCIVOLETTO, SANDRA; BUSATTO, GERALDO F.; NUNES, PAULA V.; CUNHA, PAULO JANNUZZI. Social skills and psychopathic traits in maltreated adolescents. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, v. 25, n. 4, p. 397-405, APR 2016. (10/15604-0, 10/15786-1, 10/18374-6, 11/19185-5)

CUNHA, PAULO JANNUZZI; DURAN, FABIO L. S.; DE OLIVEIRA, PAULA APPROBATO; CHAIM-AVANCINI, TIFFANY M.; MILIONI, ANA LUIZA V.; OMETTO, MARIELLA; SQUARZONI, PAULA; SANTOS, PEDRO P.; CAETANO, SHEILA C.; BUSATTO, GERALDO F.; et al. Callosal abnormalities, altered cortisol levels, and neurocognitive deficits associated with early maltreatment among adolescents: A voxel-based diffusion-tensor imaging study. BRAIN AND BEHAVIOR, JAN 2021. (10/18374-6, 10/15786-1, 11/19185-5, 10/15604-0)

PAULO JANNUZZI CUNHA; PAULA APPROBATO DE OLIVEIRA; MARIANA CORTEZZI; GERALDO F. BUSATTO; SANDRA SCIVOLETTO. DISFUNÇÃO EXECUTIVA E BAIXO DESEMPENHO ESCOLAR EM ADOLESCENTES USUÁRIOS DE DROGAS COM HISTÓRIA DE MAUS-TRATOS. MedicalExpress (São Paulo, online), v. 2, n. 6, 2015-12-00. (10/15604-0, 10/18374-6, 10/15786-1)

CUNHA, PAULO JANNUZZI; DURAN, FABIO L. S.; DE OLIVEIRA, PAULA APPROBATO; CHAIM-AVANCINI, TIFFANY M.; MILIONI, ANA LUIZA V.; OMETTO, MARIELLA; SQUARZONI, PAULA; SANTOS, PEDRO P.; CAETANO, SHEILA C.; BUSATTO, GERALDO F.; et al. Callosal abnormalities, altered cortisol levels, and neurocognitive deficits associated with early maltreatment among adolescents: A voxel-based diffusion-tensor imaging study. BRAIN AND BEHAVIOR, v. 11, n. 3, p. 9-pg., 2021-01-15. (10/15604-0, 11/19185-5, 10/18374-6, 10/15786-1)