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Analysis of physical, mechanical and antibacterial properties of infiltrant materials related the composition: base monomers, diluents and antimicrobial

Grant number: 10/20254-9
Support Opportunities:Regular Research Grants
Start date: April 01, 2011
End date: March 31, 2013
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal Investigator:Regina Maria Puppin Rontani
Grantee:Regina Maria Puppin Rontani
Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil

Abstract

The use of sealants in pits and fissures in partnership with educational and preventive programs has been a very effective measure in preventing tooth decay. However, the arrest of incipient caries, especially in the interproximal regions, has proved a major challenge for dentistry becoming less invasive. The development of light-curing resins that infiltrate in non-cavitated lesions could lead to an arrest of lesion progression in order to preserve as much a tooth structure. The addition of antibacterial quaternary monomers in the composition of infiltrants can increase the effectiveness of these materials in relation to inhibit the growth of cariogenic microorganisms without producing change in the structure of the polymer. This study aims to assess the degree of conversion, hardness and contact angle of the resin monomers TEGDMA and UDMA associated with ethanol 20% and HEMA, as well as evaluating the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of antibacterial monomer methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB) which will be incorporated into the resin mixture. The results may contribute to the development of a new dental material of great use in pediatrics and preventive programs. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
INAGAKI, LUCIANA TIEMI; BRUSCHI ALONSO, ROBERTA CAROLINE; SPAGNOLO ARAUJO, GIOVANA ALBAMONTE; CARUALHO DE SOUZA-JUNIOR, EDUARDO JOSE; ANIBAL, PAULA CRISTINA; HOFLING, JOSE FRANCISCO; PASCON, FERNANDA MIORI; PUPPIN-RONTANI, REGINA MARIA. Effect of monomer blend and chlorhexidine-adding on physical, mechanical and biological properties of experimental infiltrants. Dental Materials, v. 32, n. 12, p. E307-E313, . (10/01010-1, 11/22149-0, 10/20254-9)