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Effect of acid demineralization of the interface on the consolidation of onlay autogenous bone grafts.

Grant number: 11/02016-6
Support type:Regular Research Grants
Duration: June 01, 2011 - August 31, 2013
Field of knowledge:Health Sciences - Dentistry - Oral and Maxillofacial Surgery
Principal researcher:Maria Lúcia Rubo de Rezende
Grantee:Maria Lúcia Rubo de Rezende
Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
Assoc. researchers:Alberto Consolaro ; Roberta Santos Domingues


Dental implants are the most used treatment for edentulous areas rehabilitation and the viability for such procedure requires sufficient bone quantity and quality. Therefore surgical techinques for alveoalr bone preservation and augentation are being developed to allow osseointegrated implants instalation. Autogenous onlay bone grafts harvested from intraoral donor sites are considered gold standard among grafting materials because fulfil the properties that favor new bone formation and interface consolidation. Concurrenttly it is important to stress that the healing process of hard tissues takes place initialy with clastic cells dufferention and acid deposition by these cells which produces surface demineralization. Considering these aspects, this study aims at verifying in rabbits if the in situ acid demineralization of bone bed and bone graft have any effect on graft consolidation when compared to conventional technique(no demineralized). Besides, it will be analised if the method for graft fixation, by screw or by gluing a non resorbable membrane over the graft with cyanoacrilate adhesive influences the graft consolidation and resorption. The results will be analised by ANOVA test of variance. (AU)

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