Interaction between innate immune receptors in the activation of macrophages and dendritic cells

• Grant number: 08/50958-8
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: August 01, 2008
• End date: July 31, 2013
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Karina Ramalho Bortoluci
• Grantee: Karina Ramalho Bortoluci
• Host Institution: Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF). Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Diadema , SP, Brazil
• Associated research grant(s): 13/50374-4 - Cell death pathways and their impact on host susceptibililty to intracelular pathogens, AP.R
• Associated scholarship(s): 12/10077-8 - Role of MYD88 and caspase-1 in the induction of autophagy and its relevance to the control of T. cruzi infection, BP.IC; 11/12639-0 - Role of inflammasomes in dendritic cell maturation and induction of adaptive responses., BP.DR; 11/08502-0 - Cell death processes involvement in the flagellin adjuvant properties, BP.DR; + associated scholarships 11/04185-0 - Role of inflammasomes in dendritic cell activation during Trypanosoma cruzi infection, BP.MS; 09/16966-6 - Molecular Pathways involved in cytosolic flagellin-induced iNOS expression: Consequences for macrophage resistance against infections., BP.DR; 09/03644-0 - Influence of extra and intracellular flagellin recognition in the regulation of macrophage pyroptosis and autophagy., BP.MS - associated scholarships

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CASSADO, ALEXANDRA DOS ANJOS; TAVARES DE ALBUQUERQUE, JOSE ANTONIO; SARDINHA, LUIZ ROBERTO; BUZZO, CARINA DE LIMA; FAUSTINO, LUCAS; NASCIMENTO, ROGERIO; GHOSN, ELIVER EID BOU; D'IMPERIO LIMA, MARIA REGINA; MOSIG ALVAREZ, JOSE MARIA; BORTOLUCI, KARINA RAMALHO. Cellular Renewal and Improvement of Local Cell Effector Activity in Peritoneal Cavity in Response to Infectious Stimuli. PLoS One, v. 6, n. 7, JUL 22 2011. (08/50958-8)

GONCALVES, VIRGINIA M.; MATTEUCCI, KELY C.; BUZZO, CARINA L.; MIOLLO, BRUNA H.; FERRANTE, DANNY; TORRECILHAS, ANA C.; RODRIGUES, MAURICIO M.; ALVAREZ, JOSE M.; BORTOLUCI, KARINA R.. NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production. PLoS Neglected Tropical Diseases, v. 7, n. 10, OCT 2013. (08/50958-8)