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Development of nanostructured surfaces, by electrochemical techniques, on biomedical titanium alloys


In order to improve the cycle of domain and nationalization of science and technology involved in research and development of titanium alloys for biomedical use, the goal of the present Project of Young Researcher, integrating different areas of Knowledge, is getting on biomedical titanium alloys, both already established and newly developed, bioactive nanostructured surfaces with advantages in functionality and compatibility when compared to usual methods of surface modification on the market. In this sense, in the present project is proposed to carry out modifications on the surface of pure Ti grade II (ASTM F67), and the alloys Ti-6Al-4V grade V (ASTM F136), Ti-6Al-7Nb (ASTM F1295 - 05) and Ti-15Mo (ASTM F2066-08), all of which materials will be obtained commercially, in order to determine the best experimental conditions to obtain nanotubes with diameters, lengths, geometries and microstructures optimized for implants applications. On the best alloys and nanostructures obtained, studies of stress corrosion cracking will be performed in media and conditions that simulate physiological environment. Finally, the bioactivity and biocompatibility of the nanostructurated surfaces will be evaluated by deposition of different phases of biological apatite (biomimetic method) on these nanostructures, and then by in vitro culture of osteoblastic cells, responsible for the formation, growth and bone regeneration. (AU)

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Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CORDOBA-TORRES, P.; OLIVEIRA, N. T. C.; BOLFARINI, C.; ROCHE, V.; NOGUEIRA, R. P.. Electrochemical impedance analysis of TiO2 nanotube porous layers based on an alternative representation of impedance data. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 737, p. 11-pg., . (12/11350-0, 12/01652-9)
CORDOBA-TORRES, P.; OLIVEIRA, N. T. C.; BOLFARINI, C.; ROCHE, V.; NOGUEIRA, R. P.. Electrochemical impedance analysis of TiO2 nanotube porous layers based on an alternative representation of impedance data. Journal of Electroanalytical Chemistry, v. 737, n. SI, p. 54-64, . (12/11350-0, 12/01652-9)
CAMPANELLI, LEONARDO CONTRI; BORTOLAN, CAROLINA CATANIO; CARVALHO PEREIRA DA SILVA, PAULO SERGIO; BOLFARINI, CLAUDEMIRO; CAMARINHO OLIVEIRA, NILSON TADEU. Effect of an amorphous titania nanotubes coating on the fatigue and corrosion behaviors of the biomedical Ti-6Al-4V and Ti-6Al-7Nb alloys. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 65, p. 542-551, . (12/11350-0, 13/04423-3, 12/01652-9)
BORTOLAN, CAROLINA CATANIO; CAMPANELLI, LEONARDO CONTRI; BOLFARINI, CLAUDEMIRO; CAMARINHO OLIVEIRA, NILSON TADEU. Fatigue strength of Ti-6A1-4V alloy with surface modified by TiO2 nanotubes formation. Materials Letters, v. 177, p. 46-49, . (12/11350-0, 13/04423-3, 12/01652-9)
CAMPANELLI, LEONARDO C.; OLIVEIRA, NILSON T. C.; DA SILVA, PAULO SERGIO C. P.; BOLFARINI, CLAUDEMIRO; PALMIERI, ANNALISA; CURA, FRANCESCA; CARINCI, FRANCESCO; MOTHEO, ARTUR J.. Fatigue resistance, electrochemical corrosion and biological response of Ti-15Mo with surface modified by amorphous TiO2 nanotubes layer. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, v. 107, n. 1, p. 86-96, . (12/11350-0, 12/01652-9, 16/12995-5)
OLIVEIRA, NILSON T. C.; VERDERIO, JULIA F.; BOLFARINI, CLAUDEMIRO. Obtaining self-organized nanotubes on biomedical Ti-Mo alloys. Electrochemistry Communications, v. 35, p. 139-141, . (12/17944-9, 12/11350-0, 12/01652-9)
CAMPANELLI, LEONARDO CONTRI; PEREIRA DA SILVA, PAULO SERGIO CARVALHO; CAMARINHO OLIVEIRA, NILSON TADEU; BOLFARINI, CLAUDEMIRO. Effect of the modification by titanium dioxide nanotubes with different structures on the fatigue response of Ti grade 2. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 20, n. 2, p. 120-124, . (16/12995-5, 12/01652-9, 13/04423-3)

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