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Analysis of the chemical signatures of particulate material emitted by different diesel / biodiesel concentrations and their toxic effects in biological systems

Grant number: 07/57747-0
Support Opportunities:Regular Research Grants
Duration: December 01, 2007 - November 30, 2009
Field of knowledge:Biological Sciences - Physiology - Physiology of Organs and Systems
Principal Investigator:Paulo Hilário Nascimento Saldiva
Grantee:Paulo Hilário Nascimento Saldiva
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Atmospheric pollution presents itself as a public health problem in industrialized urban centers, with the ever increasing presence of automobiles and industries as polluting sources. The effects on health have been intensively studied in recent years, demonstrating that exposure to atmospheric pollutants has been responsible for an increase in morbid-mortality and in hospitalizations due to cardio-respiratory problems and cancer. The adoption of programs of alternative fuels, such as alcohol in the decade of the 70s and nowadays biodiesel, has as one of its objectives the reduction in the emission of atmospheric pollutants, as well as the minimization of its toxic effects on health. Thus this work intends to analyze the chemical composition of the combustible material of the following fuels: diesel (2000ppm and 500ppm of sulfur) and biodiesel (B5, B20, B100) correlating the effects with health, with a view to providing data on the advantages and disadvantages of the use of these alternative fuels for the elaboration of public policies which aim for an improvement in the quality of the air and in the life of the population. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BRITO, JOSE MARA; BELOTTI, LUCIANO; TOLEDO, ALESSANDRA C.; ANTONANGELO, LEILA; SILVA, FLAVIO S.; ALVIM, DEBORA S.; ANDRE, PAULO A.; SALDIVA, PAULO H. N.; RIVERO, DOLORES H. R. F.. Acute Cardiovascular and Inflammatory Toxicity Induced by Inhalation of Diesel and Biodiesel Exhaust Particles. TOXICOLOGICAL SCIENCES, v. 116, n. 1, p. 67-78, . (07/57747-0)

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