Effect of a high fat diet ingestion on regulatory aspects of hematopoiesis in a Wistar rat model

• Grant number: 12/07572-7
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2012
• End date: July 31, 2014
• Field of knowledge: Health Sciences - Medicine - Pathological Anatomy and Clinical Pathology
• Principal Investigator: Ricardo Ambrósio Fock
• Grantee: Ricardo Ambrósio Fock
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Edgar Julian Paredes-Gamero ; Marcelo Macedo Rogero ; Primavera Borelli Garcia

Abstract

The body fat increase can generate various inflammatory mediators, that are capable to influence the proliferation and differentiation of hematopoietic cells and consequently modulate the complex regulation of the hematopoiesis. In this study we have proposed to evaluate the obesity effects in some aspects of the hematopoiesis regualtions. (AU)