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Influence of genetic and mutations polymorphisms in the development of prostate cancer hereditary

Grant number: 12/19258-5
Support type:Regular Research Grants
Duration: March 01, 2013 - February 28, 2015
Field of knowledge:Health Sciences - Medicine - Surgery
Principal researcher:Miguel Srougi
Grantee:Miguel Srougi
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Assoc. researchers:Kátia Ramos Moreira Leite ; Sabrina Thalita dos Reis Faria


The purpose of this study is to analyze the profile of Single Nucleotide Polymorphisms (SNP) between patients with and without prostate cancer with a history of hereditary disease and control group. The first group will provide patients with prostate cancer, members of families with two or more relatives affected by the disease and at least one first degree, or a relative who has been diagnosed before 55 years of age, the second will consist of patients healthy without prostate cancer, members of families with two or more relatives affected by the disease and at least one first-degree and the control group will consist of patients with CP with no family history. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
REIS, SABRINA T.; VIANA, NAYARA I.; LEITE, KATIA R. M.; DIOGENES, ERICO; ANTUNES, ALBERTO A.; ISCAIFE, ALEXANDRE; NESRALLAH, ADRIANO J.; PASSEROTTI, CARLO C.; SROUGI, VICTOR; PONTES-JUNIOR, JOSE; SALLES, MARY ELLEN; NAHAS, WILLIAM C.; SROUGI, MIGUEL. Role of Genetic Polymorphisms in the Development and Prognosis of Sporadic and Familial Prostate Cancer. PLoS One, v. 11, n. 12 DEC 1 2016. Web of Science Citations: 1.

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