The antioxidant response of the liver of male Swiss mice raised on a AIN 93 or commercial diet

• Grant number: 13/01298-3
• Support Opportunities: Regular Research Grants - Publications - Scientific article
• Start date: March 01, 2013
• End date: August 31, 2013
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Principal Investigator: Severino Matias de Alencar
• Grantee: Severino Matias de Alencar
• Host Institution: Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil

Abstract

Reactive oxygen species (ROS) are formed under natural physiological conditions and are thoughtto play an important role in many human diseases. A wide range of antioxidants are involved in cellular defense mechanisms against ROS, which can be generated in excess during stressful conditions, these include enzymes andnon-enzymatic antioxidants. The aim of this study was to evaluate the antioxidant responses of mice to two diets control, commercial and the purified AIN 93 diet, commonly used in experiments with rodents. (AU)