Energetic homeostasis and sugar signaling: diversification of the molecular mechanisms involved in the control of the energetic balance in angiosperms

• Grant number: 08/52071-0
• Support type: Program for Research on Bioenergy (BIOEN) - Thematic Grants
• Duration: October 01, 2009 - September 30, 2014
• Field of knowledge: Biological Sciences - Genetics - Plant Genetics
• Principal Investigator: Michel Georges Albert Vincentz
• Grantee: Michel Georges Albert Vincentz
• Home Institution: Centro de Biologia Molecular e Engenharia Genética (CBMEG). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated scholarship(s): 14/05957-4 - Regulation of mRNA stability in the central pathway of abscisic acid signaling, BP.MS; 14/04117-2 - The role of the transcription factor AtbZIP63 in the interaction between carbohydrates and the circadian clock in Arabidopsis thaliana, BP.PD; 12/22125-7 - Involvement of post-transcriptional regulatory pathways in ABA and glucose signaling: fast-adaptive responses to stress conditions and development control, BP.PD; + associated scholarships 12/09351-8 - Protein stability evaluation of transcription factor AtbZIP63 in biotic/abiotic stress responses and the role of this gene in resistance of Arabidopsis thaliana to Pseudomonas syringae pv tomato strain DC3000, BP.PD; 11/24090-3 - Energetic homeostasis and sugar signaling: diversification of the molecular mechanisms involved in the control of the energetic balance in angiosperms, BP.PD; 11/06413-0 - Epigenetic regulation of QQS (At3g30720) along Arabidopsis thaliana development and in response to environmental signals, BP.DR; 10/02440-0 - The role of AtbZIP63 in the control of the energy balance in Arabidopsis thaliana: identification of the target genes and partial evaluation of the functional redundancy, BP.DR - associated scholarships

Abstract

To optimize their growth and development, plants, as sessile organisms, have developed a range of efficient mechanisms to sense and respond adequately to ever changing environmental conditions. The production of sugar through photosynthesis primarily relies on light accessibility. These photosynthetic-derived sugars represent important signals, which, in combination with developmental and other environmental cues, such as mineral nutrition, water availability or pathogens attacks, influence the use of energy resources to ensure survival and propagation. Interaction between developmental, hormonal and sugar regulatory signals is deeply involved in growth control and ultimately in biomass production. The molecular mechanisms responsible for the cross talk between these different signaling pathways and their diversification in plants still need to be further elucidated to better understand plant growth patterns and biomass production. Overall, the present proposal aims at unraveling new mechanistic aspects of sugar signal transduction in plants. More specifically, we intend to: 1) define the diversification of glucose-and sucrose-induced gene expression programs among angiosperms (sugar cane, rice and Arabidopsis); 2) evaluate and describe glucose-mediated mRNA stability; 3) characterize the function of bZIP transcription factors mediating glucose-related processes; 4) provide new insight into mannose signaling. We anticipate that the data will improve our view of sugar signaling and energy homeostasis control in plants and the results will be integrated into data bases that could feed projects related to biomass and bioenergy research. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FRANK, ALEXANDER; MATIOLLI, CLEVERSON C.; VIANA, AMERICO J. C.; HEARN, TIMOTHY J.; KUSAKINA, JELENA; BELBIN, FIONA E.; NEWMAN, DAVID WELLS; YOCHIKAWA, ALINE; CANO-RAMIREZ, DORA L.; CHEMBATH, ANUPAMA; CRAGG-BARBER, KESTER; HAYDON, MICHAEL J.; HOTTA, CARLOS T.; VINCENTZ, MICHEL; WEBB, ALEX A. R.; DODD, ANTONY N. Circadian Entrainment in Arabidopsis by the Sugar-Responsive Transcription Factor bZIP63. Current Biology, v. 28, n. 16, p. 2597+, AUG 20 2018. Web of Science Citations: 20.

DUARTE, GUSTAVO TURQUETO; MATIOLLI, CLEVERSON CARLOS; PANT, BIKRAM DATT; SCHLERETH, ARMIN; SCHEIBLE, WOLF-RUEDIGER; STITT, MARK; VICENTINI, RENATO; VINCENTZ, MICHEL. Involvement of microRNA-related regulatory pathways in the glucose-mediated control of Arabidopsis early seedling development. Journal of Experimental Botany, v. 64, n. 14, p. 4301-4312, NOV 2013. Web of Science Citations: 9.

VICENTINI, R.; DEL BEM, L. E. V.; VAN SLUYS, M. A.; NOGUEIRA, F. T. S.; VINCENTZ, M. Gene Content Analysis of Sugarcane Public ESTs Reveals Thousands of Missing Coding-Genes and an Unexpected Pool of Grasses Conserved ncRNAs. TROPICAL PLANT BIOLOGY, v. 5, n. 2, p. 199-205, JUN 2012. Web of Science Citations: 12.