Clinical applications and optimization of polymeric gel dosimetry technique

• Grant number: 14/03370-6
• Support Opportunities: Regular Research Grants
• Start date: November 01, 2014
• End date: April 30, 2017
• Field of knowledge: Physical Sciences and Mathematics - Physics
• Principal Investigator: Juliana Fernandes Pavoni
• Grantee: Juliana Fernandes Pavoni
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated researchers: Oswaldo Baffa Filho

Abstract

Advances in the treatment techniques with ionizing radiation are resulting in complex dose distributions that are increasingly conforming the target volumes while sparing the normal tissues around it. However, if these treatments are not implemented and not applied correctly, they can result in serious consequences to the patient. Thus, security and quality control procedures of the modern technologies are being stimulated and it can be observed that the advances in the treatment techniques are not followed by compatible advances in the radiation dosimetry techniques, that nowadays are limited to measure dose in one or two dimensions only. A new dosimetric technique that can contribute to quality control the modern technologies used in radiation therapy, representing the necessary advance in this field and that is presenting a great development is the polymeric gel dosimetry. This technique allows tridimensional measurement of the dose distributions, is tissue equivalent, does not present angular dependence with the direction of the incident radiation and presents a high spatial resolution. The aim of this work is to apply MAGIC-f dosimetry with dose distribution measured by magnetic resonance imaging to clinical problems, measuring complex dose distributions obtained in radiotherapy by several conformational techniques, aiding the implementation and quality control of modern technologies in radiotherapy. Moreover, the optimization of this technique will be realized, with special focus in the dosimeter composition, the protocols of image acquisition and imaging processing of the acquired images. (AU)

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LIZAR, JESSICA CAROLINE; VOLPATO, KARINA CRISTINA; BRANDAO, FERNANDA CALIXTO; GUIMARAES, FLAVIO DA SILVA; ARRUDA, GUSTAVO VIANI; PAVONI, JULIANA FERNANDES. Tridimensional dose evaluation of the respiratory motion influence on breast radiotherapy treatments using conformal radiotherapy, forward IMRT, and inverse IMRT planning techniques. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, v. 81, p. 60-68, JAN 2021. (14/03370-6)

SILVEIRA, M. A.; PAVONI, J. F.; BAFFA, O.. Three-dimensional quality assurance of IMRT prostate plans using gel dosimetry. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, v. 34, p. 1-6, FEB 2017. (14/03370-6)

PAVONI, JULIANA FERNANDES; PIMENTA NEVES-JUNIOR, WELLINGTON FURTADO; DA SILVEIRA, MATHEUS ANTONIO; KALIL HADDAD, CECILIA MARIA; BAFFA, OSWALDO. Evaluation of a composite Gel-Alanine phantom on an end-to-end test to treat multiple brain metastases by a single isocenter VMAT technique. Medical Physics, v. 44, n. 9, p. 4869-4879, SEP 2017. (14/03370-6)

ACURIO, ERICK SEBASTIAN RUNDO; LIZAR, JESSICA CAROLINE; ARRUDA, GUSTAVO VIANI; PAVONI, JULIANA FERNANDES. Technical Note: Three-dimensional QA of simultaneous integrated boost radiotherapy treatments by a dose-volume histogram methodology and its comparison with 3D gamma results. Medical Physics, v. 48, n. 6, MAY 2021. (14/03370-6)

RESENDE, THIAGO DIAS; LIZAR, JESSICA CAROLINE; DOS SANTOS, FRED MULLER; BORGES, LEANDRO FEDERICHE; PAVONI, JULIANA FERNANDES. Study of the formulation optimization and reusability of a MAGAT gel dosimeter. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, v. 63, p. 105-111, JUL 2019. (14/03370-6)