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Prospective study in humans employing implants with different surface treatments installed in the jaw with delayed loading and prosthetic protocol


The rehabilitation of edentulous areas with dental implants is a process with high predictability and well documented in the literature . However , that success depends on the basis of already established osseointegration highlighting that study, the physicochemical properties of the surface , which interfere with biological responses and consequent bone repair of bone / implant interface . The purpose of this research is to analyze prospectively and compared in total edentulous mandible of humans, stability, survival rate and peri-implant bone stability of implants with different surface treatments . Twenty patients without systemic involvement , nonsmokers and edentulous will be selected . These patients will undergo surgical procedure for the installation of four implants of 4.0 x 10 mm , between mentuals foramina , one implant each surface randomly distributed per patient : ( 1 ) modified by LASER beam surface , ( 2 ) modified by LASER with the biomimetic apatite deposition method , ( 3 ) modified by double etching and ( 4 ) modified by sandblasting and acid etching ( SLA Active , Straumman ) . Clinic, resonance frequency ( Osstell ® ) , radiographic and tomographic : the analysis will be employed . After 3 months the installation of the prosthesis of the lower protocol type will be performed . Clinical , radiographic and resonance frequency ( Osstell ® ) will be analyzed in periods T0 ( immediately after implant placement ) , T1 (15 days ) , T2 (30 days) , T3 (60 days) , T4 (90 days) , T5 (180 days ) , T6 ( 360 days ) post- implant placement . The tomographic analysis will be performed in T0 , T2 , T6 periods . Quantitative data will be submitted to the Kolmogorov -Smirnov test adopting a significance level of 5 % . (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DOS SANTOS, MARCIO LUIZ; RICCARDI, CARLA DOS SANTOS; DE ALMEIDA FILHO, EDSON; GUASTALDI, ANTONIO C.. Biomimetic calcium phosphates-based coatings deposited on binary Ti-Mo alloys modified by laser beam irradiation for biomaterial/clinical applications. MRS ADVANCES, v. 3, n. 30, p. 1711-1718, . (14/05626-8)
GUASTALDI, FERNANDO P. S.; QUEIROZ, THALLITA P.; MARQUES, DANIELA O.; SANTOS, ANNE B. S.; MOLON, RAFAEL S.; MARGONAR, ROGERIO; GUASTALDI, ANTONIO C.. Comparative Evaluation of Implants with Different Surface Treatments Placed in Human Edentulous Mandibles: A 1-Year Prospective Study. JOURNAL OF MAXILLOFACIAL & ORAL SURGERY, . (14/05626-8)

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