Edwin Alexander Yates | University Liverpool - Inglaterra

• Grant number: 15/50412-9
• Support Opportunities: Research Grants - Visiting Researcher Grant - International
• Start date: July 01, 2016
• End date: August 31, 2016
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Agreement: CONFAP ; Newton Fund, with FAPESP as a partner institution in Brazil
• Principal Investigator: Marcelo Andrade de Lima
• Grantee: Marcelo Andrade de Lima
• Visiting researcher: Edwin Alexander Yates
• Visiting researcher institution: University of Liverpool , England
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• City of the host institution: São Paulo

Abstract

Studying polysaccharide-protein interactions under physiological conditions by conventional techniques is challenging. Ideally, macromolecules could be followed by both in vitro spectroscopy experiments and in tissues using microscopy, to enable a proper comparison of results, 19F labelling of glycosaminoglycan's provides background-free signals with potential in both 19F-Nuclear Magnetic Ressonance (NMR) protein-binding studies and non-linear microscopy. (AU)