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Study of dynamic thermal-mechanical behavior of polymeric hydrogels films for application as future biocompatible materials


The project has as main objective study the thermodynamic behavior of polymeric films mechanic and hydrogels films aimed at future applications such as biomaterials. Syntheses of hydrogels will be realized from modification of commercial cellulose acetate (CA) with degree of substitution (GS) 2.5. The hydrogels are obtained through esterification and crosslinking reactions between hydroxyl groups of CA and ethylenediamine tetraacetate (EDTAD). After the synthesis, the hydrogels will be analyzed and characterized by severall important techiniques. The biocompatibility studies will be the main intended application of gels. Our research group presents its experience in synthesis and preparation of biomaterials in the form of films. So little expressive the biomaterials are characterized according to their mechanical properties, being almost exclusively focused on studies of cell growth assay, biocompatibility, controlled release, among others. Very little has been published taking into consideration the relationship between thermomechanical-properties and biocompatibility in general. Thus, our research group has as main objective to study the biocompatibility of the films that will be prepared in this project and go a little further, consider the possible application of the materials on the basis of their thermodynamic properties. (AU)

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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FONTAINE, P.; WEISS-HORTALA, E.; BOTARO, V.; PAIVA, J. M. F.; SOUDAIS, Y. Impact of Atmosphere on Recovered Carbon Fibers From Poly Ether Ether Ketone (PEEK) Based Composites During Thermoconversion. WASTE AND BIOMASS VALORIZATION, v. 12, n. 12, SI, p. 6389-6402, DEC 2021. Web of Science Citations: 0.
PEREIRA ARAUJO, LUISA CARVALHO; YAMAJI, FABIO MINORU; LIMA, VITOR HUGO; BOTARO, VAGNER ROBERTO. Kraft lignin fractionation by organic solvents: Correlation between molar mass and higher heating value. Bioresource Technology, v. 314, OCT 2020. Web of Science Citations: 0.
MATOS DE FREITAS, ROBERTA RANIELLE; DO CARMO, KARINA PALMIZANI; RODRIGUES, JESSICA DE SOUZA; DE LIMA, VITOR HUGO; DA SILVA, JOELEN OSMARI; BOTARO, VAGNER ROBERTO. Influence of alkaline treatment on sisal fibre applied as reinforcement agent in composites of corn starch and cellulose acetate matrices. PLASTICS RUBBER AND COMPOSITES, v. 50, n. 1 SEP 2020. Web of Science Citations: 0.
MELERO, ANNA; SENNA, ANDRE; DOMINGUES, JULIANA; MOTTA, ADRIANA; HAUSSEN, MOEMA; RIUL JUNIOR, ANTONIO; DUEK, ELIANA; BOTARO, VAGNER. Chelating Effect of Cellulose Acetate Hydrogel Crosslinked with EDTA Dianhydride Used as a Platform for Cell Growth. ADVANCES IN MATERIALS SCIENCE AND ENGINEERING, v. 2019, SEP 15 2019. Web of Science Citations: 0.

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