Structural studies of water dispersion of lipids by X-ray scattering techniques: advances in data analysis by the Genfit software

• Grant number: 16/25847-4
• Support Opportunities: Research Grants - Visiting Researcher Grant - International
• Start date: March 06, 2017
• End date: April 05, 2017
• Field of knowledge: Biological Sciences - Biophysics - Molecular Biophysics
• Principal Investigator: Rosangela Itri
• Grantee: Rosangela Itri
• Visiting researcher: Francesco Spinozzi
• Visiting researcher institution: Università Politecnica delle Marche (UNIVPM), Italy
• Host Institution: Instituto de Física (IF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The current project consists in the development of new strategies/methodologies to interpret SAXS data from model membrane through scattering density distribution of chemical groups. In particular, there will be addressed open problems as lipid oxidation, membrane proteins and pores, as well as polydispersion of multilamellar vesicles. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE ROSA, RAFFAELA; SPINOZZI, FRANCESCO; ITRI, ROSANGELA. Hydroperoxide and carboxyl groups preferential location in oxidized biomembranes experimentally determined by small angle X-ray scattering: Implications in membrane structure. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1860, n. 11, p. 2299-2307, NOV 2018. (12/50680-5, 16/25847-4, 14/02511-5)