Betalains: structure-property relationships

• Grant number: 16/21445-9
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2017
• End date: February 28, 2019
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Erick Leite Bastos
• Grantee: Erick Leite Bastos
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Frank Herbert Quina ; Mauricio da Silva Baptista
• Associated research grant(s): 17/50130-9 - Bioinspired photoactive electron donors, AP.R SPRINT

Abstract

This research project aims to relate the chemical structures of betalains with their physicochemical properties and photochemical targeting biotechnological applications. We intent to clarify: i) how structural changes affect the physico-chemical and photochemical properties of substituted aryl betalains, ii) how to increase the cross section of two-photon absorption of artificial betalains in water, iii) what is the best method for preparation quasibetalains and how substituents modulate their color, and iv) how structural changes affect the internalization and compartmentalization of betalains in living cells. (AU)

Scientific publications

(11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

NAKASHIMA, KARINA K.; BASTOS, ERICK L.. Rationale on the High Radical Scavenging Capacity of Betalains. ANTIOXIDANTS, v. 8, n. 7, JUL 2019. (13/24964-9, 14/22136-4, 16/21445-9, 19/06391-8)

GONCALVES, LETICIA C. P.; LOPES, NATHANA B.; AUGUSTO, FELIPE A.; PIOLI, RENAN M.; MACHADO, CAROLINE O.; FREITAS-DORR, BARBARA C.; SUFFREDINI, HUGO B.; BASTOS, ERICK L.. Phenolic betalain as antioxidants: meta means more. Pure and Applied Chemistry, v. 92, n. 2, p. 243-253, FEB 2020. (14/22136-4, 07/59407-1, 16/21445-9, 15/24760-0)

QUINA, FRANK H.; BASTOS, ERICK L.. Chemistry Inspired by the Colors of Fruits, Flowers and Wine. Anais da Academia Brasileira de Ciências, v. 90, n. 1, 1, p. 681-695, 2018. (16/21445-9)

REIS, JOEL S.; FERNANDES, ARTHUR B.; FREITAS-DORR, BARBARA C.; BASTOS, ERICK L.; STEFANI, HELIO A.. Oxazoline as acceptor moiety for excited-state intramolecular proton transfer. Tetrahedron, v. 74, n. 48, p. 6866-6872, NOV 29 2018. (14/22136-4, 15/25629-4, 14/10563-5, 17/24821-4, 16/02392-1, 16/21445-9)

ESKILDSEN PAGANO, ANA PAULA; KHALID, NAUMAN; KOBAYASHI, ISAO; NAKAJIMA, MITSUTOSHI; NEVES, MARCOS ANTONIO; BASTOS, ERICK LEITE. Microencapsulation of betanin in monodisperse W/O/W emulsions. Food Research International, v. 109, p. 489-496, JUL 2018. (14/22136-4, 16/21445-9)

ESTEVES, LARISSA C.; PINHEIRO, AMANDA C.; PIOLI, RENAN M.; PENNA, TATIANA C.; BAADER, WILHELM J.; CORRERA, THIAGO C.; BASTOS, ERICK L.. Revisiting the Mechanism of Hydrolysis of Betanin. Photochemistry and Photobiology, v. 94, n. 5, p. 853-864, SEP-OCT 2018. (15/18474-4, 14/22136-4, 15/08539-1, 14/15962-5, 16/21445-9)

PIOLI, RENAN MORAES; MATTIOLI, RENAN RODINI; ESTEVES, LARISSA CERRATO; DOCHEV, STEFAN; BASTOS, ERICK LEITE. Comparison of the effect of N-methyl and N-aryl groups on the hydrolytic stability and electronic properties of betalain dyes. DYES AND PIGMENTS, v. 183, p. 7-pg., 2020-12-01. (14/22136-4, 16/21445-9, 17/20133-6, 19/06391-8)

BASTOS, ERICK LEITE; FARAHANI, POORIA; BECHARA, ETELVINO J. H.; BAADER, WILHELM JOSEF. Four-membered cyclic peroxides: Carriers of chemical energy. JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, v. 30, n. 9, SI, SEP 2017. (14/22136-4, 16/21445-9, 15/02314-8)

BASTOS, ERICK LEITE; FARAHANI, POORIA; BECHARA, ETELVINO J. H.; BAADER, WILHELM JOSEF. Four-membered cyclic peroxides: Carriers of chemical energy. JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, v. 30, n. 9, p. 18-pg., 2017-09-01. (15/02314-8, 16/21445-9, 14/22136-4)

FREITAS-DORR, B. C.; MACHADO, C. O.; PINHEIRO, A. C.; FERNANDES, A. B.; DORR, F. A.; PINTO, E.; LOPES-FERREIRA, M.; ABDELLAH, M.; SA, J.; RUSSO, L. C.; et al. A metal-free blue chromophore derived from plant pigments. SCIENCE ADVANCES, v. 6, n. 14, APR 2020. (18/25842-8, 14/10563-5, 16/21445-9, 15/25629-4, 14/22136-4, 19/06391-8, 15/24760-0, 15/18474-4)

BELTRAN RODRIGUES, ANA CLARA; AFONSO MARIZ, INES DE FATIMA; SENGO MACOAS, ERMELINDA MARIA; TONELLI, RENATA ROSITO; GASPAR MARTINHO, JOSE MANUEL; QUINA, FRANK HERBERT; BASTOS, ERICK LEITE. Bioinspired water-soluble two-photon fluorophores. DYES AND PIGMENTS, v. 150, p. 105-111, MAR 2018. (14/22136-4, 16/21445-9)