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Vaccinia virus in blood samples of humans, domestic and wild mammals in Brazil

Grant number: 18/00693-0
Support Opportunities:Regular Research Grants - Publications - Scientific article
Start date: April 01, 2018
End date: September 30, 2018
Field of knowledge:Health Sciences - Collective Health - Public Health
Principal Investigator:Jane Megid
Grantee:Jane Megid
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Outbreaks of Vaccinia virus (VACV) affecting cattle and humans have been reported in Brazil in the last 15 years, but the origin of outbreaks remains unknown. Although VACV DNA have been already detected in mice (Mus musculus), opossums (Didelphis albiventris) and dogs during VACV zoonotic outbreaks, no transmission to cattle or humans from any of these were reported during Brazilian outbreaks. In this work, we assessed the PCR positivity to VACV in blood samples of cows and other domestic mammals, wild rodents and other wild mammals, and humans from areas with or without VACV infection reports. Our results show the detection of VACV DNA in blood samples of cows, horse and opossums, raising important questions about VACV spread. (AU)

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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)