Association of SNPs in candidate genes and chromosomal regions with thickness of subcutaneous fat in Canchim cattle

• Grant number: 06/06237-9
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: June 01, 2007
• End date: June 30, 2010
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
• Principal Investigator: Luciana Correia de Almeida Regitano
• Grantee: Gisele Batista Veneroni
• Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil

Abstract

The Canchim breed has been used in the beef cattle industry as an alternative for production intensification. However, this breed has less fat thickness. For this reason, researches have been carried with the objective of increasing the fat deposition in this breed, including the search for molecular markers that aid the identification of the animals with greater genetic potential for this trait. To better incorporate the molecular genetics to the breeding programs, the association between molecular markers and production traits need to be evaluated in the population in study. In several bovine population, the centromeric region of chromosome 14 (BTA14) was related with fat deposition, besides in the Canchim population that will be used in this study. Among the genes located in this region, the Acyl CoA Synthetase 3 gene (ACSL3), related to the metabolism of fatty acid and the Development and Differentiation Enhancing Factor 1 gene (DDEF1), related to the adipogenesys, can be pointed as potentials candidates to influence the genetic variation for fat deposition. The scope of this work is the identification of polymorphisms in ACSL3 and DDEF1 genes, as well as the association of these polymorphisms with the fat thickness of bovine of the Canchim breed.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VENERONI-GOUVEIA, G.; TIZIOTO, P. C.; MEIRELLES, S. L. C.; SANTIAGO, A. C.; ALENCAR, M. M.; REGITANO, L. C. A.. Candidate genes for carcass traits in a tropical-adapted Brazilian composite beef breed. Genetics and Molecular Research, v. 14, n. 4, p. 16667-16674, 2015. (06/06237-9, 13/17778-4)