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Genome wide association study in Nellore cattle for quantitative and qualitative characteristics of carcass and meat

Grant number: 13/23946-7
Support type:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): February 14, 2014
Effective date (End): August 10, 2014
Field of knowledge:Agronomical Sciences - Animal Husbandry
Principal Investigator:Carmen Josefina Contreras Castillo
Grantee:Anirene Galvão Tavares Pereira
Supervisor abroad: Tad Stewart Sonstegard
Home Institution: Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil
Local de pesquisa : Beltsville Agricultural Research Center, United States  
Associated to the scholarship:13/02552-0 - Genome association study in Nellore cattle for quantitative and qualitative characteristics of carcass and meat, BP.DR

Abstract

The cattle industry is one of the main highlights of the Brazilian agribusiness on the world stage, with Brazil holds the second largest herd effective in the world, with about 200 million head, and the great expanse of Brazilian territory generates products with varying quality, from prime cuts until meats valued less. The end of the 80 marks the generation of tools for animal breeding and the last wave of technological innovation represents a revolution bringing methodologies to identify and characterize SNP markers so mass. Thus, it becomes possible to identify predictors of quality and increased understanding of the biology of muscle, this knowledge has implications for improving the quality characteristics such as pH, water holding capacity, color, smoothness, covering fat and marbling. Another important perspective of application of genomic knowledge is the identification and mapping of genes that influence the expression of economically important traits, statistical associations between genomic loci and hundreds of complex traits, increasing the understanding of important molecular pathways and biological. Thus, the objective of this study is to generate knowledge about the mechanisms involved in the manifestation of qualitative and quantitative characteristics related to carcass and meat from Nellore cattle from the previous survey of quality characteristics of 667 cattle, assessed values pH, loin eye area and fat thickness, marbling, maturity, color, weight loss and cooking drip and shear force. The DNA samples of the animals will be genotyped to determine the single-site polymorphisms and correlated quality characteristics through genome association study by GWAS. Expected to identify chromosomal regions associated with phenotypic characteristics studied, showing genes and variants that act in the processes related to meat quality in cattle zebu, this knowledge with potential biotechnological applications to improve the quality of meat. (AU)