Comparison of muscle fatigue developed by femoral quadriceps and deltoid medium and its time to recovery in patients with chronic obstructive pulmonary disease

• Grant number: 09/03586-0
• Support Opportunities: Scholarships in Brazil - Master
• Start date: March 01, 2010
• End date: December 31, 2010
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Simone Dal Corso
• Grantee: Eduardo Foschini Miranda
• Host Institution: Universidade Nove de Julho (UNINOVE). Campus Memorial. São Paulo , SP, Brazil

Abstract

The peripheral muscle dysfunction is a common finding in patients with COPD, but the structural changes and functional damage does not appear to be homogeneous among skeletal muscles of the upper and lower members. The fatigue of the quadriceps after exercise in COPD has been widely studied in the literature, but no studies analyzing the fatigue of upper members and comparing it to fatigue in lower members.In this context, the aim was to compare the fatigue developed by middle deltoid and femoral quadriceps of COPD patients in submaximal load equivalent, and, secondarily, to examine the recovery time of the fatigue of these muscles.Will be selected 18 patients (sample size calculation) with moderate to severe obstruction (FEV1 <70% of predicted) and stable disease. Patients perform: test of maximum voluntary contraction (CMV) in the femoral quadriceps (QF) and middle deltoid (MD), sustained isometric contraction (CIS) for 20 seconds with 60% of CVM to the concurrent record of electromyography, endurance testing of the QF and DM with 60% of the load from the CVM and again by the CIS with 20 seconds to record electromyographic fatigue verification of the QF and DM.Subsequently, the electromyographic variables will be compared before and after the protocol of each muscle to endurance and magnitude of fatigue and his time of recovery of MD and QF are compared with each other.The importance of comparing the fatigue of different body segments in COPD is not only to differentiate the macrostructural changes of muscles, but provide support for the physiological understanding of possible mechanisms of improvement pre-and post-intervention, because the training upper and lower members are essential components of the program of rehabilitation in COPD patients. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

EDUARDO FOSCHINI MIRANDA; CARLA MALAGUTI; SIMONE DAL CORSO. Disfunção muscular periférica em DPOC: membros inferiores versus membros superiores. Jornal Brasileiro de Pneumologia, v. 37, n. 3, p. 380-388, 2011-06-00. (09/03586-0)