Blood pressure response during resistance exercise in hypertensive patients: influence of amlodipine.ABSTRACT Currently, resistance exercise has been recommended as a complement to aerobic exercise for hypertensive people. However, achieving this type of exercise promotes a large increase in blood pressure in these subjects. In previous study found that the beta blocker, atenolol, by decreasing the heart rate, can reduce the hypotensive response before this type of exercise. However, the effect of antihypertensive drugs tha thave the peripheral effect on this response have not been investigated. Thus, the aims of this study will be test whether the antagonist calcium channel, amlodipine , reduces the increase in blood pressure during resistance exercise in hypertensive individuals. To do so will have ten essential hypertensive patients (blood pressure between 140/90 and 160/105 mmHg) between 30 and 60 years old, without injury to the target organ, which will be submitted blindly to 2 periods of 6 weeks using placebo and amlodipine (5 or 10 mg - 2x/day). In each phase, volunteers will do, stress test, measures blood pressure control and protocol extension legs to exhaustion at 40%, 80% and 100% of 1RM. Blood pressure is measured by intra-arterial technique throughout the protocol. The results will be compared by analysis of variance (ANOVA) of two factors for repeated samples with 2 main factors. Be accepted as a significant content of P <0.05 and when necessary, will be used post-hoc Newman-Keuls. Keywords: Hypertension, antagonist calcium channel, resistance exercise.
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