| Grant number: | 18/12390-1 |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| Start date: | October 01, 2018 |
| End date: | February 20, 2022 |
| Field of knowledge: | Health Sciences - Physical Education |
| Principal Investigator: | Cláudia Lúcia de Moraes Forjaz |
| Grantee: | Rafael Yokoyama Fecchio |
| Host Institution: | Escola de Educação Física e Esporte (EEFE). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated scholarship(s): | 19/22829-3 - Effect of post-resistance exercise hypotension on cerebral hemodynamics and its regulation, BE.EP.DR |
Abstract The effect of Dynamic Resistance Training (DRT) on Blood Pressure (BP) is controversial, with some studies suggesting a significant reduction. Meanwhile, other studies indicate an important hypotensive effect of Isometric Resistance Training (IRT), but these findings in hypertensive individuals are restricted to IRT with handgrip (IRT_h), which has limited musculoskeletal benefits. Thus, the combination of IRT_h and DRT in a Combined Resistance Training protocol (CRT) could potentiate the hypotensive effect of Resistance Training (RT) and promote global musculoskeletal benefits. Thus, the objective of this study will be to evaluate and compare, in hypertensive patients, the effects of DRT, IRT_h, CRT on resting BP and its mechanisms, as well as on the response of these variables after an acute RT session and on muscle strength. For this purpose, 80 medicated hypertensive men will be randomized to 4 groups: DRT (8 resistance exercises, 3 sets until moderate fatigue with 50-60% of 1RM), IRT_h (4 sets of 2 min of handgrip with 30% of MVC), CRT (DRT followed by IRT_h) and control (CON-30 min of stretching exercises). Interventions will be conducted 3x / week for 10 weeks. Pre- and post-interventions, muscle strength, BP (auscultatory, photoplethysmographic and 24h), its systemic hemodynamic mechanisms (CO2 rebreathing), local hemodynamics mechanisms (blood flow and flow mediated dilatation by ultrasonography) and autonomic mechanisms (variability of heart rate and blood pressure) will be evaluted before and after a resistance exercise session performed with the training protocol of each group (DRT, IRT_h and CRT) and after a rest period sitting in the CON group. For data analysis will be used the mixed ANOVAs with the post-hoc test of Newman-Keuls and adopting a value of p> 0.05. (AU) | |
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