Evaluation of cytotoxic, antigenotoxic, antimutagenic and anticarcinogenic activities of Solanum lycocarpum and its majoritary compounds on in vitro and in vivo mammalian cells

• Grant number: 09/15871-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: March 01, 2010
• End date: February 28, 2013
• Field of knowledge: Biological Sciences - Genetics - Mutagenesis
• Principal Investigator: Denise Crispim Tavares Barbosa
• Grantee: Carla Carolina Munari
• Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; LIMA CAMPOS, JACQUELINE COSTA; LIMA MARTINS, SABRINA DE PAULA; DA COSTA, JULIANA CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. Antiproliferative activity of Solanum lycocarpum alkaloidic extract and their constituents, solamargine and solasonine, in tumor cell lines. Journal of Natural Medicines, v. 68, n. 1, p. 236-241, JAN 2014. (09/15871-1, 11/05732-4)

MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; DE SOUZA LIMA, ILDERCILIO MOTA; LIMA MARTINS, SABRINA DE PAULA; DA COSTA, JULIANA DE CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells. Food and Chemical Toxicology, v. 50, n. 10, p. 3696-3701, OCT 2012. (09/15871-1, 11/05732-4)

TAVARES, DENISE CRISPIM; MUNARI, CARLA CAROLINA; DE FREITAS ARAUJO, MARCELO GONZAGA; BELTRAME, MARIANA CORREA; FURTADO, MICHELLE ANDRADE; GONCALVES, CAMILA COSTA; JORGE TIOSSI, RENATA FABIANE; BASTOS, JAIRO KENUPP; CUNHA, WILSON ROBERTO; SOLA VENEZIANI, RODRIGO CASSIO. Antimutagenic Potential of Solanum lycocarpum against Induction of Chromosomal Aberrations in V79 Cells and Micronuclei in Mice by Doxorubicin. Planta Medica, v. 77, n. 13, p. 1489-1494, SEP 2011. (09/15871-1, 07/07211-6)

MUNARI, CARLA CAROLINA; DE OLIVEIRA, POLLYANNA FRANCIELLI; LEANDRO, LUIS FERNANDO; PIMENTA, LEANDRA MARA; FERREIRA, NATALIA HELEN; DA COSTA, JULIANA DE CARVALHO; BASTOS, JAIRO KENUPP; TAVARES, DENISE CRISPIM. In Vivo Assessment of Genotoxic, Antigenotoxic and Anticarcinogenic Activities of Solanum lycocarpum Fruits Glycoalkaloidic Extract. PLoS One, v. 9, n. 11, NOV 18 2014. (09/15871-1, 11/05732-4)