|Support type:||Scholarships in Brazil - Doctorate|
|Effective date (Start):||May 01, 2010|
|Effective date (End):||February 28, 2014|
|Field of knowledge:||Biological Sciences - Ecology - Applied Ecology|
|Principal researcher:||Eliana Reiko Matushima|
|Home Institution:||Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil|
Chelonia mydas, called green sea turtle, feeds and nests in Brazilian coast. The fibropapillomatosis, disease characterized by benign skin tumors (fibropapillomas), is one of the most threats against this species. Studies suggest relations between a specific virus and environmental and genetic factors. Will be studied green sea turtles with and without fibropapillomas from Brazilian areas. Biometric data, numbers and distributions of tumors by anatomic regions will be noted and will be take blood sample. The aims are (1) to asses leukocyte activity by flow cytometry: Phagocytosis stimulated by Zymosan A (Saccharomyces cerevisiae) Bio Particles®, Alexa Fluor® 594 conjugate and oxidative burst - basal and stimulated by PMA (phorbol miristate-acetate);(2) to investigate polychorinated biphenyls (PCBs) in blood samples; (3) to establish correlations between PCBs and cell activity of non-affected and affected turtles from study areas. The fibropapillomatosis is still unclear and affect many juvenils green sea turtles. Diseases related with pollution are a relevant factor for the ecosystem imbalance.