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Comparison of the effects of the feeding beta-glucan supplementation and the use of oxytetracycline on hematological, immune and productive responses and meat residue depletion in tilapia reared in net cages

Grant number: 10/14679-7
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2011
Effective date (End): February 28, 2013
Field of knowledge:Agronomical Sciences - Fishery Resources and Fishery Engineering - Aquaculture
Principal researcher:Fabiana Pilarski
Grantee:Nycolas Levy Pereira
Home Institution: Centro de Aquicultura (CAUNESP). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


The impact caused by the chemotherapics and antimicrobians use in animal production has been studied in the last few years. Data such as environmental degradation, high costs for the producer, rising of resistant cepa to the active principles and residues in the meat are among the most common findings. The same is found in fish farming. The fish handling causes high level of stress and damage the immune function in fish. To avoid the appearance of diseases, the producers use antibiotics in the feed and in the water. Substances known as immunostimulant enhance the immune responses of fish. These substances can decrease or even avoid the use of chemotherapics in fish production. The aim of this research is to compare the utilization of an antimicrobian (Oxytetracycline) and an immunostimulant (²-glucan) in tilapia feeding in net cages. Zoothecnical (growth, weight gain and condition factor), physiological (blood glucose, cortisol, total protein levels, blood cells counting, hematocrit, hemoglobin concentration and hematimetric indices) and immune (lysozyme, complement and leukocyte respiratory activity) indicators and residue depletion in water and meat will be determined. The appropriate alternatives development in fish farming might help to reduce costs regarding the quality of final product and also reduce the indiscriminate use of antimicrobians and chemotherapics in fish productive chain besides to prevent environmental impacts and high costs.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
VALLADAO, G. M. R.; LEVY-PEREIRA, N.; VIADANNA, P. H. O.; GALLANI, S. U.; FARIAS, T. H. V.; PILARSKI, F. Haematology and histopathology of Nile tilapia parasitised by Epistylis sp., an emerging pathogen in South America. BULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS, v. 35, n. 1, p. 14-20, 2015. Web of Science Citations: 3.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
PEREIRA, Nycolas Levy. Beta-glucano e mananoligossacarídeo na alimentação de tilápias-do-nilo (Oreochromis niloticus) sobre as respostas hematológica, imunológica e desempenho produtivo. 2013. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.

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