Chronic wounds are a major source of morbidity-mortality; therefore, they have a significant impact on public health and the expenditure of healthcare resources. Some authors describe the presence of intrinsic (friction, pressure) and extrinsic factors (stillness, bad skin perfusion) to the pressure ulcers (PU) development. Bacterial cellulose (BC) membrane is used for treatment of burn injury or skin ulcers due to its amazing body conformation, keeping the humidity, reducing the pain and accelerating the healing process. The antibacterial effects of propolis and low-level laser therapy (LLLT) are confirmed, and LLLT also promoves the ulcer healing, pain relief, better local circulation and reducing inflammation. Objective: Compare the effectiveness of pure or propolis BC membrane curative application, associated or not to LLLT in individuals who have PU. Methods: 50 patients will participate of this study, and they will be divided in 5 groups: Pure BC Membrane Group, Propolis BC Membrane Group, Laser Group, Pure BC Membrane + Laser Group, Propolis BC Membrane + Laser Group. BC membrane will be exchanged every week until the moment of the cure, or no later than 90 days. Laser applications will be made twice a week until the moment of the cure, or no later than 90 days. Pacients will be divided between groups randomly. Ulcers assessments will be carried with regards to its aspects, diameter and depth, thru a digital caliper rule and a camera. Expected results: Is expected that the association between pure or propolis BC and LLLT increases the regenerative effects of the injured tissue.
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