Study of the functional cycle of the Hsp90 molecular chaperone of protozoa and of the action of the co-chaperone Activator of the Hsp90 ATPase Activity - AHA1

• Grant number: 10/19242-6
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): April 01, 2011
• Effective date (End): August 31, 2015
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Principal Investigator: Julio Cesar Borges
• Grantee: Thiago Vargas Seraphim
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated scholarship(s): 14/06829-0 - Comparative functional studies of the activator of Hsp90 ATPase 1 (AHA1) of Leishmania braziliensis and Plasmodium falciparum by yeast complementation assays, BE.EP.DR

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SERAPHIM, THIAGO V.; ALVES, MARINA M.; SILVA, INDJARA M.; GOMES, FRANCISCO E. R.; SILVA, KELLY P.; MURTA, SILVANE M. F.; BARBOSA, LEANDRO R. S.; BORGES, JULIO C.. Low Resolution Structural Studies Indicate that the Activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis Has an Elongated Shape Which Allows Its Interaction with Both N- and M-Domains of Hsp90. PLoS One, v. 8, n. 6, JUN 24 2013. (11/23110-0, 08/09025-8, 12/50161-8, 12/01953-9, 10/19242-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SERAPHIM, Thiago Vargas. Structural studies of the Aha1 cochaperone (Activator of Hsp90 ATPase 1) from Leishmania braziliensis and its action on the Hsp90 functional cycle.. 2015. Doctoral Thesis - Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC/BT) São Carlos.