Aminoacid metabolism and aging in Saccharomyces cerevisiae

• Grant number: 11/13506-4
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: September 01, 2011
• End date: March 31, 2013
• Field of knowledge: Biological Sciences - Biochemistry - Metabolism and Bioenergetics
• Principal Investigator: Alicia Juliana Kowaltowski
• Grantee: Phillipe Pessoa de Santana
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 10/51906-1 - Mitochondrial bioenergetics, ion transport, redox state and DNA metabolism, AP.TEM

Abstract

S. cerevisiae are an interesting experimental model to study aging and the beneficial effects of calorie restriction. We recently found, using proteomics, that calorie restriction and aging significantly change the expression of proteins related to aminoacid metabolism. This project aims to study the effects of calorie restriction and aging on aminoacid metabolism. (AU)