High blood pressure and aggregation of risk factors in adolescents: a multicenter study

• Grant number: 11/11137-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: October 01, 2011
• End date: November 30, 2014
• Field of knowledge: Health Sciences - Collective Health - Preventive Medicine
• Principal Investigator: Heraclito Barbosa de Carvalho
• Grantee: Augusto César Ferreira de Moraes
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 11/20662-2 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study, BE.EP.DR

Abstract

The objectives are: (i) estimate the prevalence of high blood pressure (HBP) in adolescents aged 13-18 years from ten countries; (ii) to analyze the sociodemographic and behavioral factors associated with this outcome. Methods: This project is a multicenter collaborative study conducted by Brazilian and Europe researchers with standardized procedures for sampling, recruitment and data collection. The school-based survey were conducted with probability sampling in high school students from Brazil and nine European countries. Brazilian data are from the research "Cardiovascular risk factors: biological and behavioral indicators" and the data from European countries are "Healthy lifestyle in Europe by nutrition in adolescence cross-sectional study". Outcome for this project is HBP, diagnosed by measuring levels of systolic and diastolic pressure by validated method for this population. The independent variables will be examined are: country, age, type of school, parental education, parental employment status, level of physical activity, sedentary behavior, eating habits, regular consumption of tobacco and drinking alcohol and nutritional status. To analyze the magnitude of associations between exposures and the outcome will be applied to Poisson regression with robust variance, through a hierarchical conceptual model will be developed.

Scientific publications

(17)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERREIRA DE MORAES, AUGUSTO CESAR; MIGUEL FERNANDEZ-ALVIRA, JUAN; CARVALHO, HERACLITO BARBOSA; MEIRHAEGHE, ALINE; DALLONGEVILLE, JEAN; KAFATOS, ANTHONY; MARCOS, ASCENSION; MOLNAR, DENES; MANIOS, YANNIS; RUIZ, JONATAN R.; et al. Physical Activity Modifies the Associations between Genetic Variants and Blood Pressure in European Adolescents. JOURNAL OF PEDIATRICS, v. 165, n. 5, p. 1046-U237, NOV 2014. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; LACERDA, MARIA BEATRIZ; MORENO, LUIS A.; HORTA, BERNARDO L.; CARVALHO, HERACLITO BARBOSA. Prevalence of High Blood Pressure in 122,053 Adolescents: A Systematic Review and Meta-Regression. MEDICINE, v. 93, n. 27, DEC 2014. (11/11137-1, 11/17211-9, 11/20662-2)

REY-LOPEZ, J. P.; DE CARVALHO, H. B.; DE MORAES, A. C. F.; RUIZ, J. R.; SJOSTROM, M.; MARCOS, A.; POLITO, A.; GOTTRAND, F.; MANIOS, Y.; KAFATOS, A.; et al. Sleep time and cardiovascular risk factors in adolescents: The HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study. Sleep Medicine, v. 15, n. 1, p. 104-110, JAN 2014. (11/11137-1, 12/05723-8, 11/20662-2)

REY-LOPEZ, J. P.; BEL-SERRAT, S.; SANTALIESTRA-PASIAS, A.; DE MORAES, A. C.; VICENTE-RODRIGUEZ, G.; RUIZ, J. R.; ARTERO, E. G.; MARTINEZ-GOMEZ, D.; GOTTRAND, F.; DE HENAUW, S.; et al. Sedentary behaviour and clustered metabolic risk in adolescents: The HELENA study. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, v. 23, n. 10, p. 1017-1024, OCT 2013. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; GUERRA, PAULO HENRIQUE; MENEZES, PAULO ROSSI. The worldwide prevalence of insufficient physical activity in adolescents; a systematic review. NUTRICION HOSPITALARIA, v. 28, n. 3, p. 575-584, MAY-JUN 2013. (11/11137-1)

RENDO-URTEAGA, TARA; CESAR FERREIRA DE MORAES, AUGUSTO; SADALLA COLLESE, TATIANA; MANIOS, YANNIS; HAGSTROMER, MARIA; SJOSTROM, MICHAEL; KAFATOS, ANTHONY; WIDHALM, KURT; VANHELST, JEREMY; MARCOS, ASCENSION; et al. The combined effect of physical activity and sedentary behaviors on a clustered cardio-metabolic risk score: The Helena study. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 186, p. 186-195, MAY 1 2015. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; CASSENOTE, ALEX JONES FLORES; LECLERCQ, CATHERINE; DALLONGEVILLE, JEAN; ANDROUTSOS, ODYSSEAS; TOEROEK, KATALIN; GONZALEZ-GROSS, MARCELA; WIDHALM, KURT; KAFATOS, ANTHONY; CARVALHO, HERACLITO BARBOSA; et al. Resting Heart Rate Is Not a Good Predictor of a Clustered Cardiovascular Risk Score in Adolescents: The HELENA Study. PLoS One, v. 10, n. 5, MAY 26 2015. (14/13367-2, 11/11137-1, 11/20662-2)

AUGUSTO CÉSAR FERREIRA DE MORAES; PAULO HENRIQUE GUERRA; PAULO ROSSI MENEZES. The worldwide prevalence of insufficient physical activity in adolescents: a systematic review. NUTRICION HOSPITALARIA, v. 28, n. 3, p. 575-584, 2013-06-00. (11/11137-1)

GRACIA-MARCO, LUIS; MORENO, LUIS A.; RUIZ, JONATAN R.; ORTEGA, FRANCISCO B.; FERREIRA DE MORAES, AUGUSTO CESAR; GOTTRAND, FREDERIC; ROCCALDO, ROMANIA; MARCOS, ASCENSION; GOMEZ-MARTINEZ, SONIA; DALLONGEVILLE, JEAN; et al. Body Composition Indices and Single and Clustered Cardiovascular Disease Risk Factors in Adolescents: Providing Clinical-Based Cut-Points. PROGRESS IN CARDIOVASCULAR DISEASES, v. 58, n. 5, p. 555-564, MAR-APR 2016. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; SIANI, ALFONSO; BARBA, GIANVINCENZO; VEIDEBAUM, TOOMAS; TORNARITIS, MICHAEL; MOLNAR, DENES; AHRENS, WOLFGANG; WIRSIK, NORMAN; DE HENAUW, STEFAAN; et al. Incidence of high blood pressure in children - Effects of physical activity and sedentary behaviors: The IDEFICS study High blood pressure, lifestyle and children. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 180, p. 165-170, FEB 1 2015. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; GOMEZ-MARTINEZ, SONIA; ANDROUTSOS, ODYSSEAS; JIMENEZ-PAVON, DAVID; SJOSTROM, MICHAEL; KAFATOS, ANTHONY; WIDHALM, KURT; CANADA, DAVID; MARTIN-MATILLAS, MIGUEL; et al. Family socioeconomic factors are negatively associated with blood pressure in European boys, but not girls, and Brazilian adolescents: Results from two observational studies. BLOOD PRESSURE, v. 24, n. 4, p. 250-257, AUG 2015. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; GRACIA-MARCO, LUIS; IGLESIA, IRIS; GONZALEZ-GROSS, MARCELA; BREIDENASSEL, CHRISTINA; FERRARI, MARIKA; MOLNAR, DENES; GOMEZ-MARTINEZ, SONIA; ANDROUTSOS, ODYSSEAS; KAFATOS, ANTHONY; et al. Vitamins and iron blood biomarkers are associated with blood pressure levels in European adolescents. The HELENA study. NUTRITION, v. 30, n. 11-12, p. 1294-1300, NOV-DEC 2014. (11/11137-1, 11/20662-2)

LIN, YI; MOURATIDOU, THEODORA; VEREECKEN, CARINE; KERSTING, MATHILDE; BOLCA, SELIN; DE MORAES, AUGUSTO CESAR F.; CUENCA-GARCIA, MAGDALENA; MORENO, LUIS A.; GONZALEZ-GROSS, MARCELA; VALTUENA, JARA; et al. Dietary animal and plant protein intakes and their associations with obesity and cardio-metabolic indicators in European adolescents: the HELENA cross-sectional study. NUTRITION JOURNAL, v. 14, JAN 21 2015. (11/11137-1, 11/20662-2)

FERRARI, M.; CUENCA-GARCIA, M.; VALTUENA, J.; MORENO, L. A.; CENSI, L.; GONZALEZ-GROSS, M.; ANDROUTSOS, O.; GILBERT, C. C.; HUYBRECHTS, I.; DALLONGEVILLE, J.; et al. Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status. European Journal of Clinical Nutrition, v. 69, n. 2, p. 247-255, FEB 2015. (11/11137-1, 11/20662-2)

CESAR FERREIRA DE MORAES, AUGUSTO; BEL-SERRAT, SILVIA; MANIOS, YANNIS; MOLNAR, DENES; KAFATOS, ANTHONY; CUENCA-GARCIA, MAGDALENA; HUYBRECHTS, INGE; SETTE, STEFANIA; WIDHALM, KURT; STEHLE, PETER; et al. Dietary protein and amino acids intake and its relationship with blood pressure in adolescents: the HELENA STUDY. EUROPEAN JOURNAL OF PUBLIC HEALTH, v. 25, n. 3, p. 450-456, JUN 2015. (11/11137-1, 11/20662-2)

FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; REY-LOPEZ, JUAN PABLO; GRACIA-MARCO, LUIS; BEGHIN, LAURENT; KAFATOS, ANTHONY; JIMENEZ-PAVON, DAVID; MOLNAR, DENES; DE HENAUW, STEFAAN; MANIOS, YANNIS; et al. Independent and Combined Effects of Physical Activity and Sedentary Behavior on Blood Pressure in Adolescents: Gender Differences in Two Cross-Sectional Studies. PLoS One, v. 8, n. 5, MAY 1 2013. (11/11137-1, 11/20662-2)

DE MORAES, A. C. F.; MUSSO, C.; GRAFFIGNA, M. N.; SOUTELO, J.; MIGLIANO, M.; CARVALHO, H. B.; BERG, G.. Prevalence of cardiovascular risk factors among Latin American adolescents: a multilevel analysis. JOURNAL OF HUMAN HYPERTENSION, v. 28, n. 3, p. 206-209, MAR 2014. (11/11137-1, 11/20662-2)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MORAES, Augusto César Ferreira de. Pressão arterial elevada e agregação de fatores  de risco em adolescentes: um estudo multicêntrico. 2014. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) São Paulo.