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Metal complexes with rimantadine: synthesis, spectroscopic characterization and citotoxic studies.

Grant number: 11/14812-1
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2011
Effective date (End): September 30, 2012
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
Principal Investigator:Pedro Paulo Corbi
Grantee:Débora Dezotti Camargo
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


This work deals with the synthesis, spectroscopic characterization and biological assays of metal complexes with rimantadine. The ligand is used as an antiviral agents against Influenza A virus. The complexes will be synthesized under aqueous and/or ethanolic solutions, characterized by a set of chemical and spectroscopic analysis, with emphasis on 1H, 13C and 15 NMR spectroscopic measurements, and evaluated as potential antiviral and antitumor agents.

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