| Grant number: | 11/15453-5 |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| Start date: | December 01, 2011 |
| End date: | November 03, 2016 |
| Field of knowledge: | Biological Sciences - Physiology - Compared Physiology |
| Principal Investigator: | Renata Guimarães Moreira Whitton |
| Grantee: | Carlos Eduardo Tolussi |
| Host Institution: | Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated research grant: | 08/57687-0 - Effects of global climate change of the Brazilian fauna: a conservation physiology approach, AP.PFPMCG.TEM |
| Associated scholarship(s): | 14/01866-4 - Evaluation of the effects of impacted environment on fish vitellogenesis, BE.EP.DR |
Abstract With the increasing flow of chemicals in aquatic environments due to human action, many species of fish are undergoing changes in several physiological processes, including reproduction, which can result in a decrease populations, or even the extinction of some species. Thus, this work aims to analyze the possible changes in the reproductive process, more precisely in vitellogenesis, as a result of exposure of fish species in impacted. For this, we will analyze the plasma concentration of the hormone 17²-estradiol, responsible for the production of vitellogenin, as well as the hepatic expression of this molecule. In addition, we will investigate a possible deviation of the mobilization of energetic substrates that are used to form the molecule of vitellogenin in response to stress, resulting from an impacted environment. These analysis will be performed by determining the concentration of energetic substrates, as well as the activity of enzymes involved in the metabolism of these substrates, oxidative stress, as well as enzymes that indicate the presence of pollutants in the environment. To carry out this work will use as experimental model, female teleosts whose species will be defined according to availability and regularity of capture in an impacted environment (Billings Reservoir) and compared to a population of animals of the same species living in an environment without the presence of pollutants (Ponte Nova Dam). According to preliminary surveys, a candidate would be initially species belonging to the genus Astyanax sp., which is distributed in both areas. (AU) | |
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