| Grant number: | 11/04868-0 |
| Support Opportunities: | Scholarships in Brazil - Master |
| Start date: | March 01, 2012 |
| End date: | September 30, 2013 |
| Field of knowledge: | Health Sciences - Medicine - Medical Clinics |
| Principal Investigator: | Jorge Simao do Rosario Casseb |
| Grantee: | Stephanie Bianca Haél Sales |
| Host Institution: | Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
Abstract Infection with Human Immunodeficiency Virus (HIV) that causes Acquired Immunodeficiency Syndrome (AIDS) is a challenge unprecedented in modern history to public health. After the HAART era the mortality due to opportunistic diseases had a major decline. However, metabolic disorders and fat redistribution (lipodystrophy), Type 2 Diabetes Mellitus and Hypertension has become the great importance in clinical practice. Nutritional intervention should be part of all programs of control and treatment of HIV / AIDS since the incidence of metabolic disturbances and loss of micronutrients can have an impact on morbidity and mortalidade. As Vitamin D deficiency is common in patients with antiretroviral ultilizam due the lower absorption, drug interaction, diarrhea and vomiting, among the complex changes to decreased bone mass is common. The study will be conducted in a cohort of 379 patients by anthropometry, laboratory analysis, food history, and quantification of micronutrients by HPLC method. Therefore, the results of this study will effectively help in the precise methods in the diagnosis and the best treatment for this situation, thereby minimizing the impact of these changes and contribute individually and collectively for their decline, promoting health and quality of life of these patients. | |
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