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PREVALENCE OF ABSORPTION AND DEFICIENCY OF VITAMIN D AND CALCIUM IN PATIENTS LIVING WITH HIV / AIDS

Grant number: 11/04868-0
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2012
Effective date (End): September 30, 2013
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal researcher:Jorge Simão do Rosário Casseb
Grantee:Stephanie Bianca Haél Sales
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Infection with Human Immunodeficiency Virus (HIV) that causes Acquired Immunodeficiency Syndrome (AIDS) is a challenge unprecedented in modern history to public health. After the HAART era the mortality due to opportunistic diseases had a major decline. However, metabolic disorders and fat redistribution (lipodystrophy), Type 2 Diabetes Mellitus and Hypertension has become the great importance in clinical practice. Nutritional intervention should be part of all programs of control and treatment of HIV / AIDS since the incidence of metabolic disturbances and loss of micronutrients can have an impact on morbidity and mortalidade. As Vitamin D deficiency is common in patients with antiretroviral ultilizam due the lower absorption, drug interaction, diarrhea and vomiting, among the complex changes to decreased bone mass is common. The study will be conducted in a cohort of 379 patients by anthropometry, laboratory analysis, food history, and quantification of micronutrients by HPLC method. Therefore, the results of this study will effectively help in the precise methods in the diagnosis and the best treatment for this situation, thereby minimizing the impact of these changes and contribute individually and collectively for their decline, promoting health and quality of life of these patients.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SALES, STEPHANIE HAEL; DA MATTA, SANDRA; DA SILVA, DANIELA CARDEAL; ASSONE, TATIANE; FONSECA, LUIZ AUGUSTO M.; DUARTE, ALBERTO J. S.; CASSEB, JORGE. High frequency of deficient consumption and low blood levels of 25-hydroxyvitamin D in HIV-1-infected adults from Sao Paulo city, Brazil. SCIENTIFIC REPORTS, v. 5, . (11/04868-0, 15/12311-6)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SALES, Stephanie Bianca Haél. Prevalence of deficiency/insufficiency in serum levels and intake of vitamin D and calcium in HIV patients. 2014. Master's Dissertation - Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) São Paulo.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.