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Effect of a bioactive glass-ceramic on enamel and root dentin erosion lesions

Grant number: 11/12160-7
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): May 01, 2012
Effective date (End): April 30, 2015
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal researcher:Fernanda de Carvalho Panzeri Pires de Souza
Grantee:Michelle Alexandra Chinelatti
Home Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


Due the absence of studies addressing the effects of bioactive glasses in erosion control and the importance and prevalence of this type of tooth wear, this study aims to evaluate in vitro the effect of applying a bioactive glass-ceramic in the control of erosion lesions in enamel and root dentin. To this end, bovine enamel and root dentin fragments (5 x 5 mm) (n = 10) will receive daily application of different surface treatments (1. Biosilicate ® 2. Acidulated phosphate fluoride, 3. Untreated) during the performance of erosive cycles (citric acid, 5 min; 1x days, 21 days). The surface of the specimens will be analyzed with a contact profilometer before the completion of cycles (baseline scan), allowing to quantify the superficial loss (um), by profilometry, in four periods of the erosive challenge: initial (1 day) and at the end of each week (7, 14 and 21 days). For the same periods, the extension in depth of erosive lesions (um) will be evaluated using confocal laser scanning, as well as crystal deposition pattern (SEM) and crystalline compounds (X-ray diffraction) formed after application of different treatments will be analyzed qualitatively.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE MORAIS, RENATA COSTA; SILVEIRA, RENATA ESPINDOLA; CHINELATTI, MICHELLE ALEXANDRA; PANZERI PIRES-DE-SOUZA, FERNANDA DE CARVALHO. Biosilicate as a dentin pretreatment for total-etch and self-etch adhesives: In vitro study. INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES, v. 70, p. 271-276, OCT 2016. Web of Science Citations: 3.

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