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Retrospective prospecting of lipids present in follicular fluid associated with the development potential of oocytes.

Grant number: 11/15416-2
Support type:Scholarships in Brazil - Master
Effective date (Start): July 01, 2012
Effective date (End): January 31, 2014
Field of knowledge:Agronomical Sciences - Veterinary Medicine
Principal researcher:Flávio Vieira Meirelles
Grantee:Gabriella Mamede Andrade
Home Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
Associated research grant:08/57877-3 - National Institute of Science and Technology in Cell Therapy, AP.TEM


The in vitro embryo production in Brazil, occupies a prominent place among the biotechnology of animal reproduction and the current challenge is to be increasingly accessible to producers, so that it is fundamental closer to the results of production and survival of embryos produced in vitro those developed naturally. Much of this variation of the potential for embryo development is related to characteristics of maternally inherited oocyte, which requires an adequate maturity to acquire the potential to develop to the blastocyst stage. So there is a possibility that that capacity is related to the lipid profile of follicular fluid. Thus, this project aims at assessing the correlation of the development potential of oocytes with the content of the lipid profile in follicular fluid, based on individual farming system and retrospective analysis of this liquid. The ions coming from the study of the follicular fluid lipid profile will be assessed against the potential of the oocyte that was contained.However, there is so far a detailed characterization of the environment this follicular oocytes are exposed.An important and often overlooked are the fluid lipids.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA SILVEIRA, JULIANO COELHO; ANDRADE, GABRIELLA MAMEDE; SIMAS, ROSINEIDE COSTA; MARTINS-JUNIOR, HELIO ALVES; EBERLIN, MARCOS NOGUEIRA; SMITH, LAWRENCE CHARLES; PERECIN, FELIPE; MEIRELLES, FLAVIO VIEIRA. Lipid profile of extracellular vesicles and their relationship with bovine oocyte developmental competence: New players in intra follicular cell communication. Theriogenology, v. 174, p. 1-8, OCT 15 2021. Web of Science Citations: 0.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
ANDRADE, Gabriella Mamede. Retrospective analysis follicular fluid lipids associated with the oocytes development potential. 2014. Master's Dissertation - Universidade de São Paulo (USP). Faculdade de Zootecnica e Engenharia de Alimentos (FZE/BT) Pirassununga.

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