EVALUATION OF ANTIMYCOBACTERIAL POTENTIAL OFESSENTIAL OILS

• Grant number: 12/06813-0
• Support type: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): July 01, 2012
• Effective date (End): December 31, 2012
• Field of knowledge: Biological Sciences - Microbiology - Applied Microbiology
• Principal researcher: Carlos Henrique Gomes Martins
• Grantee: Jessica Aparecida Alves
• Home Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Abstract

The searching for natural compounds active has increased significantly in recent years, some of these compounds are able to eliminate mycobacteria. The use of plants by the man in the cure of many diseases is a millenary practice and it's still used nowadays. The plants are considered true complex biochemical laboratories that, among several compounds, synthetize the natural active principle. The present project aims to assess the activity of essential oils against Mycobacterium avium, Mycobacterium tuberculosis and Mycobacterium kansasii. To evaluate the antimycobacterial activity the broth microdilution method (REMA) will be used for determining the MIC. Therefore, this project aims to collaborate with information that enables future studies for developing new therapeutic agents against infections caused by pathogenic mycobacteria and potentially pathogenic.