Development of new polymeric scaffolds by electrospinning technique with incorpora...
| Grant number: | 12/15773-2 |
| Support type: | Scholarships in Brazil - Scientific Initiation |
| Effective date (Start): | October 01, 2012 |
| Effective date (End): | March 31, 2013 |
| Field of knowledge: | Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials |
| Principal Investigator: | Anderson de Oliveira Lobo |
| Grantee: | Mustafa Mohamed Zogbi Junior |
| Home Institution: | Instituto de Pesquisa e Desenvolvimento (IP&D). Universidade do Vale do Paraíba (UNIVAP). São José dos Campos , SP, Brazil |
| Associated research grant: | 11/17877-7 - Development of new polymeric scaffolds by electrospinning technique with incorporation of vertically aligned carbon nanotubes and nanohidroxyapatite for bone tissue regeneration, AP.JP |
Abstract Vertically aligned multiwalled carbon nanotubes (VACNT) is of particular interest in regenerative medicine. Template-induced nanohydroxyapatite (HAp) has broad prospects in applied fields of bone regenerative medicine. Thus, it becomes very attractive a combination these two excellent materials to bone tissue engineering applications. VACNT films were produced as a thin film, using a microwave plasma chamber at 2.45GHz on Ti substrates (10mmx10mmx1mm). Superhydrophilic VACNT (VACNT-O2) films were obtained by the incorporation of oxygen-containing groups using a pulsed-direct current plasma reactor with pure oxygen. The electrodeposition of the nHAp crystals on the VACNT-O2 films will be perform using Ca(NO3)2.4.H2O (2,5 mM) + NH4H2PO4 (1,5 mM). The electrochemical measurements will be performing using a three-electrode cell coupled to an Autolab PGSTAT128N equipment. VACNT-O2 films will be use as working electrode, and the geometric area in contact with electrolytic solution. A platinum coil wire served as auxiliary electrode, and an Ag/AgCl electrode will be used as reference electrode. The electrodeposition parameters will be variable with different data, such as: electrolyte temperature (23-90ºC); Time (20-120 minutes); pH (4,2-7,4). Field emission gun, micro X-ray fluorescence spectrometer by energy-dispersive, X-ray diFfractogram, Raman spectroscopy will be use for characterization. | |